About My Health Careers Internship MedBlogs Contact us

Here's What causes Acute Flaccid Myelitis

by Hannah Joy on February 27, 2018 at 5:32 PM
Font : A-A+

Here's What causes Acute Flaccid Myelitis

Enterovirus D68 (EV-D68) was discovered to be the most likely cause of Acute Flaccid Myelitis (AFM). AFM is a rare illness that affects the nervous system of children.

The research was published in The Lancet Infectious Diseases. The widespread outbreak of the respiratory virus in 2014 and 2016, which was accompanied by increased cases of AFM, suggests a need for better preparation for the disease's possible return in 2018 and beyond.


The team of doctors and scientists were from the U.S. and Europe led by Kevin Messacar, MD, an infectious disease specialist from Children's Hospital Colorado (Children's Colorado).

"What started as a mystery illness that was causing sudden paralysis in children is now much better understood," said Dr. Messacar. "Accumulated evidence which supports Enterovirus D68 as a likely cause of acute flaccid myelitis will advance prevention and treatment efforts."

The published study in The Lancet Infectious Diseases is the culmination of approximately three years of scientific research to better understand this condition.

The rapid progress is in part due to a unique partnership on Colorado's Anschutz Medical Campus, in which the front-line clinicians were able to move extremely quickly from clinical observation and alerting the Centers for Disease Control and Prevention to laboratory studies to investigate the relationship between EV-D68 and AFM.

As a major referral center for the seven-state region, Children's Colorado doctors not only recognized the first cluster of this disease in 2014, but also were able to study the virus with colleagues from the University of Colorado School of Medicine, including Ken Tyler, MD, an expert in neurovirology and chair of the department of neurology.

"When cases came into the hospital, I was able to use current samples to inject the virus into lab research mice," said Dr. Tyler. "This laboratory model allowed us to quickly study how the virus infects the spinal cord and will help us test which treatments will be most beneficial for patients."

In addition to the multitude of cases of EV-D68 and associated AFM that were observed in patients from across the U.S. in 2014 and 2016, this condition now has been documented across the world in 14 countries and on six continents.

As such, Dr. Messacar is working with collaborators to improve awareness, enhance surveillance and pursue investigations to guide new approaches to prevention and treatment.

"Our work has been driven and continues to be inspired by the patients and families affected by this illness. Their participation in these research efforts will no doubt help children for years to come," said Dr. Messacar.

Source: Eurekalert

News A-Z
News Category
What's New on Medindia
Printed Temperature Sensors help with Continuous Temperature Monitoring
Health Benefits of Giloy
Breast Cancer Awareness Month 2021 - It's time to RISE
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

Recommended Reading
Dangerous Food Additives
Find out how food additives for almost every food that you consume come with danger signals and ......
Antibody Therapy To Detect Disease Progression of Alzheimer’s, Nervous Disorders
Administering HJ8.5 antibody increased the detectable levels of tau protein in the serum of ......
RNA Binding Protein may Contribute to Nervous Disorders
Misplacement of TDP-43 in nerve cells is a hallmark of ALS and other neurological disorders and ......
Colombia Declares an End to the Mosquito-Borne Zika Epidemic
Colombia declared that its Zika epidemic is over, but warned that the mosquito-borne virus would ......

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use