About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Heavy Drinking Weakens Body's Ability to Fight Infections

by VR Sreeraman on September 19, 2009 at 1:59 PM
Font : A-A+

 Heavy Drinking Weakens Body's Ability to Fight Infections

Binge drinking can weaken body's ability to fight off infections for at least 24 hours afterwards, finds a new study.

Stephen Pruett, currently at the College of Veterinary Medicine at Mississippi State University, USA and Ruping Fan of Louisiana State University Health Sciences Centre, USA, focused their study on the effect of heavy drinking on toll-like receptor 4 (TLR4), a protein that has an important role in immune system activation.

Advertisement

Previous research has shown that too much alcohol inhibits the body's production of pro-inflammatory cytokines, which are signalling molecules that launch the inflammatory response to infection.

The new study conducted over mouse model has confirm that acute alcohol exposure prevents the body from producing certain key pro-inflammatory cytokines.
Advertisement

The researchers found that ethanol molecules suppress TLR4's usual ability to send signals that would normally trigger the production of inflammatory cytokines.

Alcohol's effects continue long after the party is over: some cytokines were still not on full duty guarding against infection 24 hours after the binge.

"The time frame during which the risk of infection is increased might be at least 24 hours," said Pruett.

"A persistent effect of ethanol on cells is indicated, such that inhibition of the response of some cytokines occurs even after the ethanol is cleared," he added.

The study is published in the open access journal BMC Immunology.

Source: ANI
LIN
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Vaccination  And Counter  Measures Against  Monkeypox
Indian Railways Special Concession on Health Grounds
COVID Toes
View all
Recommended Reading
News Archive
Date
Category
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Alcoholic Liver Disease Diet Lifestyle and Heart Disease Alcohol Addiction and Women Healthy Living 

Most Popular on Medindia

Post-Nasal Drip Hearing Loss Calculator Iron Intake Calculator Indian Medical Journals Diaphragmatic Hernia How to Reduce School Bag Weight - Simple Tips Calculate Ideal Weight for Infants Sinopril (2mg) (Lacidipine) Selfie Addiction Calculator Sanatogen

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
ASK A DOCTOR ONLINE