Heart Failure Treatment Effective With Umbilical Cord Stem Cells

by Julia Samuel on  September 27, 2017 at 5:31 PM Genetics & Stem Cells News
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Treatment with umbilical cord-derived stem cells for heart failure can lead to notable improvements in heart muscle function and quality of life, according to a new study published in Circulation Research.
Heart Failure Treatment Effective With Umbilical Cord Stem Cells
Heart Failure Treatment Effective With Umbilical Cord Stem Cells

"We are encouraged by our findings because they could pave the way to a non-invasive, promising new therapy for a group of patients who face grim odds," said study corresponding author Fernando Figueroa, M.D., professor of medicine at the Universidad de los Andes in Chile.

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In this trial, 30 patients, ages 18 to 75, with stable heart failure receiving optimal drug therapy underwent intravenous infusions with either umbilical cord-derived stem cells or placebo. The umbilical cords were obtained from full-term human placentas from healthy donors by cesarean section after informed consent.

Compared to the placebo treatment, the stem cell therapy:


    Heart failure, marked by the heart muscle's inability to pump blood efficiently, affects some 37 million people worldwide. Despite medical advances, half of patients diagnosed with heart failure will die within five years of diagnosis, according to Figueroa. If affirmed in larger studies, these findings could provide a promising new treatment option for a condition that currently has few.

    Source: Eurekalert

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