Highlights
- Older adults who live in long-term care facilities are at high risk for respiratory infections because their immune response tends to be weaker.
- Monthly high dose of //vitamin D reduced the number of respiratory infections in older adults.
Participants in the study included 107 adults, aged 60 and older, who lived in long-term care facilities in Colorado. Half the group members (also known as the "high-dose group") who were already taking zero to 1,000 International Units (or IUs, a measurement for vitamins) per day of vitamin D and got an additional dose of 100,000 IU of vitamin D once a month.
The other half of the group (also known as the low-dose group) received a placebo (a pill that has no effect and includes no active medication) once a month depending on how much vitamin D they took daily or monthly.
Researchers counted the number of acute respiratory infections needing medical attention (common colds, sinusitis, middle ear infections, acute bronchitis, influenza, and pneumonia) that participants experienced during the study's 12-month follow-up period. The researchers also counted falls, fractures, kidney stones, hospitalizations, and deaths during the study period.
The researchers reported that people in the high-dose vitamin D group had 40 percent fewer respiratory infections during the 12-month follow-up period compared to people in the low-dose group. However, the people in the high-dose group had more than twice the number of falls compared to people in the low-dose group.
More study is needed to see whether daily (rather than monthly) dosing with high levels of vitamin D could help protect older adults from respiratory infections and minimize the risk of falls, said the researchers.
- Adit A. Ginde et al., High-Dose Monthly Vitamin D for Prevention of Acute Respiratory Infection in Older Long-Term Care Residents: A Randomized Clinical Trial, Journal of the American Geriatric Society (2016) 10.1111/jgs.14679.
Source-Medindia