Highlights:
Depression is one of the common and serious mood disorder that affect millions of people around the world. It can occur at any age and usually worsen conditions like diabetes and heart diseases.//
According to the World Health Organisation, around 350 million people suffer due to depression.
Number of antidepressants are prescribed for the treatment. And many FDA drugs are found to cause serious side effects.- Depression is a common mood disorder affecting millions of people around the world.
- Antidepressant drugs are prescribed for the treatment of depression.
- A Research team from Texas Tech Health Science Center discovered Bupropion its metabolite to block serotonin type 3A receptors.
Bupropion
This medication is prescribed for depression and smoking cessation. It increases the levels of certain chemicals in the brain and reduces the cravings, anxiety, irritability and other symptoms associated with depression.
This medication is prescribed for depression and smoking cessation. It increases the levels of certain chemicals in the brain and reduces the cravings, anxiety, irritability and other symptoms associated with depression.
‘New findings related to antidepressant drugs may show promise in treating depression.’
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A research team from Texas Tech Health Science Center led by Michaela Jansen, Pharm.D., Ph.D., recently examined the ability of bupropion and its metabolite to block the action of serotonin type 3A receptor (5HT3ARs).Previous studies on Bupropion were based on the discovery of reuptake inhibitors as molecular targets for the drug within the brain network and in 1999 the drug was also found to inhibit nicotinic receptors and block smoking cessation.
The recent study of the drug was published in the september issue of the journal Neuropharmacology.
Depression Screening Test
Online Depression Screening Test tells if you have mild or chronic depression based on your depression symptoms. Learn how to deal with depression by using this self-assessment calculator.
Online Depression Screening Test tells if you have mild or chronic depression based on your depression symptoms. Learn how to deal with depression by using this self-assessment calculator.
Akash Pandhare, M.D., Ph.D, author and scientist at the TTUHSC Department of Cell Physiology and Molecular Biophysics, "For a long time, the blockade of dopamine and norepinephrine reuptake by the antidepressant bupropion within the hypofunctioning central nervous system monoamine systems has remained one of the pharmacological underpinnings for its therapeutic efficacy."
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Quiz on Antidepressants
The use of antidepressants is quite common with an increase in stress-related depression of the modern world. The tricyclic antidepressants like amitriptyline and imipramine are among the older drugs for the treatment of depression. Newer drugs like the selective serotonin reuptake inhibitors (SSRIs) and the atypical antidepressants like mianserin and mirtazapine result in lesser side effects. Test your knowledge on antidepressants by taking this quiz.
The use of antidepressants is quite common with an increase in stress-related depression of the modern world. The tricyclic antidepressants like amitriptyline and imipramine are among the older drugs for the treatment of depression. Newer drugs like the selective serotonin reuptake inhibitors (SSRIs) and the atypical antidepressants like mianserin and mirtazapine result in lesser side effects. Test your knowledge on antidepressants by taking this quiz.
The research findings were also found to demonstrate clinical relevant concentration of receptor blockade by both the drug and its metabolite. The findings will now be a part of the pharmacy and medical text books.
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Prescriptions For Anti-depressants And Diabetes Drugs On The Rise In U.K
Prescriptions dished out for depression and diabetes have almost doubled in the past decade.
Prescriptions dished out for depression and diabetes have almost doubled in the past decade.
Source-Medindia
