Obesity in Adolescence Affects Cognitive Function In Midlife

Highlights

A high body mass index in adolescence affects brain function later in midlife.
Low economic position during childhood had an influence in the adverse effect on the cognitive function.
Taller stature in both sexes and late growth in women were associated with better midlife cognitive performance.

Obesity in Adolescence Affects Cognitive Function In Midlife

Overweight and obesity in adolescents have increased substantially and affect a third of the adolescent population in some developed countries. The association of adolescent BMI with cognitive function in midlife has been studied by the scientists at the Hebrew University-Hadassah Braun School of Public Health and Community Medicine.

The researchers used weight and height data from 507 individuals tracked from over 33 years starting at age 17. The participants completed a computerized cognitive assessment at ages 48-52, and their socioeconomic position was assessed by multiple methods. Using mixed models the researchers calculated the life-course burden of BMI from age 17 to midlife, and used multiple regression to assess associations of BMI and height with global cognition.

Alzheimers Disease
Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and making the person increasingly dependent on others.

‘Childhood household socioeconomic position appears to strongly modify the association between adolescent BMI and poorer cognition in midlife.’

In the population-based study of a Jerusalem cohort, followed longitudinally from adolescence for over 33 years, the findings point out that higher BMI in late adolescence and the long-term cumulative burden of BMI predicted poorer cognitive function later in life.

"Importantly, this study shows that an impact of obesity on cognitive function in midlife may already begin in adolescence, independently of changes in BMI over the adult life course," said the paper's senior author, Prof. Jeremy Kark of the Hebrew University-Hadassah Braun School of Public Health and Community Medicine.

Childhood Obesity
Childhood obesity is one of the most serious health challenges in the developing countries and needs to be understood and tackled effectively.

"Our results also show that taller stature was associated with better global cognitive function, independent of childhood and adult socioeconomic position, and that height increase in late adolescence, reflecting late growth, conferred a protective effect, but among women only," added Irit Cohen-Manheim, doctoral candidate at the Braun School and lead author.

The researchers point out that while socioeconomic position may have a particularly important role in the trajectory of a person's lifetime cognitive function, it has rarely been adequately taken into account.

Prof. Kark said, "Our results are consistent with the hypothesis that childhood living conditions, as reflected also by height, influence cognitive function later in life; however, our study is unique in showing that an adverse association of higher BMI with cognitive function appears to begin in adolescence and that it appears to be restricted to adults with lower childhood socioeconomic position."

"Evidence for the association between impaired cognitive function in midlife and subsequent dementia supports the clinical relevance of our results. Findings of the relation of BMI in adolescence with poorer midlife cognitive status, particularly in light of the ongoing epidemic of childhood obesity, require confirmation," said Irit Cohen-Manheim.

Reference

Prof. Jeremy Kark et al., Body Mass Index, Height, and Socioeconomic Position in Adolescence, Their Trajectories into Adulthood, and Cognitive Function in Midlife , Journal of Alzheimer's Disease (2016), http:content.iospress.com/articles/journal-of-alzheimers-disease/jad160843.

Source: Medindia

Dementia
Dementia has become a very big concern as we have an aging population across the world. Dementia is also terrifying to us because of its disturbing symptoms and limited treatment options.

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Julia Samuel. (2016, December 09). Obesity in Adolescence Affects Cognitive Function In Midlife. Medindia. Retrieved on May 22, 2022 from https://www.medindia.net/news/healthwatch/obesity-in-adolescence-affects-cognitive-function-in-midlife-166018-1.htm.
MLA

Julia Samuel. "Obesity in Adolescence Affects Cognitive Function In Midlife". Medindia. May 22, 2022. <https://www.medindia.net/news/healthwatch/obesity-in-adolescence-affects-cognitive-function-in-midlife-166018-1.htm>.
Chicago
Julia Samuel. "Obesity in Adolescence Affects Cognitive Function In Midlife". Medindia. https://www.medindia.net/news/healthwatch/obesity-in-adolescence-affects-cognitive-function-in-midlife-166018-1.htm. (accessed May 22, 2022).
Harvard
Julia Samuel. 2021. Obesity in Adolescence Affects Cognitive Function In Midlife. Medindia, viewed May 22, 2022, https://www.medindia.net/news/healthwatch/obesity-in-adolescence-affects-cognitive-function-in-midlife-166018-1.htm.