About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Nanotherapeutics: Innovative Way of Delivering Drug to Cancerous Tumor
Advertisement

Nanotherapeutics: Innovative Way of Delivering Drug to Cancerous Tumor

Font : A-A+

Highlights
  • Scientists have developed an innovative technique that involves a unique way of delivering drugs to a tumor directly.
  • The new technique damages only the tumor and spares the nearby tissues.

An innovative way of delivering a drug to a tumor by attaching it to a blood cell has been demonstrated by a research team from the Washington State University.

The research team reported the new technique in the journal Advanced Materials.

Advertisement

Nanotherapeutics: Innovative Way of Delivering Drug to Cancerous Tumor

The discovery could help doctors to target tumors with anticancer drugs, without damaging the healthy tissues.

Developing Treatment Using Nanotherapeutic Particle
A research team led by Zhenjia Wang, assistant professor of Pharmaceutical sciences was found to work with nanotherapeutic particles which were so small that 1000 of them would fit across the size that equals to the width of a hair.
Advertisement

Attaching a nanoscale particle to a white blood cell would help a drug to move past the armor of blood vessels that shield the tumor. This is found to be a major challenge in nanotechnology drug delivery.

Gold Nanoparticles Implanted on a Tumor
Wang implanted a tumor on the flank of a mouse. The tumor was then exposed to near infra-red radiation which causes inflammation and releases proteins to attract white blood cells called neutrophils into the tumor.

The mouse was then injected with gold nanoparticles treated with antibodies. When the tumor was exposed to infrared light, the interaction of gold particles along with light was found to produce heat to kill the tumor cells, Wang said.

Further studies would involve attaching an anticancer drug doxorubicin along with the nanoparticle. This could help them to deliver the drug directly to the tumor and avoid damaging the nearby tissues.

Wang said, "We have developed a new approach to deliver therapeutics into tumors using the white blood cells of our body."

"This will be applied to deliver many anticancer drugs, such as doxorubicin, and we hope that it could increase the efficacy of cancer therapies compared to other delivery systems."

References
  1. Dafeng Chu, Xinyue Dong, Qi Zhao, Jingkai Gu, Zhenjia Wang. Photosensitization Priming of Tumor Microenvironments Improves Delivery of Nanotherapeutics via Neutrophil Infiltration. Advanced Materials, 2017; 1701021 DOI: 10.1002/adma.201701021


Source: Medindia

Citations   close

Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Get Involved and Stand Up for Human Rights on Human Rights Day 2022
Coronary Artery Bypass Grafting
Macronutrients Calculator for Weight Loss
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Toxicity Ganglion Cysts - Ganglion Wrist Signature Drug Toxicity Tumor Markers For Cancer Diagnosis and Prognosis Drugs Banned in India 

Most Popular on Medindia

Drug Side Effects Calculator Daily Calorie Requirements Drug Interaction Checker Loram (2 mg) (Lorazepam) Pregnancy Confirmation Calculator Blood Donation - Recipients Iron Intake Calculator Blood - Sugar Chart Find a Doctor Selfie Addiction Calculator
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Nanotherapeutics: Innovative Way of Delivering Drug to Cancerous Tumor Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests