A New study finds that living with a dog early in life may protect kids from eczema, especially those with a higher genetic risk.
- Living with a dog in early life may protect children from developing eczema
- The protective effect was strongest in children with the IL-7R gene variant linked to eczema
- Dog-related molecular signals may reduce inflammation instead of triggering allergic reactions in children who are at risk
Gene-Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies
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Man’s best friend may also be a child’s first shield against eczema #doglovers #eczema #immunehealth #petbenefits #geneticsandhealth #medindia’





What Is Eczema and Why Are Some Children More Prone?
Eczema is a chronic skin condition that causes dryness, itching, and inflammation. It typically starts in childhood and may persist for life. While both genes and environmental factors play a role, the way they interact has remained unclear until now.Some children are genetically predisposed to eczema. Researchers have identified several gene variants linked to the condition, including one near the IL-7R (interleukin-7 receptor) gene, which helps regulate immune responses. Children with this variant are at higher risk of developing eczema.
The Study That Sniffed Out a Surprising Link
In the largest study of its kind, researchers from the University of Edinburgh, Bristol, Helmholtz Munich, and other institutions analyzed data from nearly 300,000 people. They examined how environmental exposures in early life, like pets, antibiotics, or siblings, interacted with 24 known eczema-related genes.The most striking finding?
Children with the IL-7R variant had a lower risk of eczema if they had a pet dog in their first year of life. In fact, the genetic risk seemed to disappear entirely in babies who regularly interacted with a dog.
How Could Dogs Possibly Help?
Lab studies confirmed that exposure to dog-related microbes and molecules in children with the IL-7R variant helped regulate overactive immune responses. Instead of triggering inflammation (which leads to eczema), these signals helped balance immune responses.Experts believe growing up around dogs introduces beneficial bacteria that could train a child’s immune system, promoting resilience rather than hypersensitivity.
What This Means for Parents and Pediatricians
Professor Sara Brown, from the University of Edinburgh’s Institute of Genetics and Cancer, explained: “This is the first study to show how exposure to a dog may help protect children from eczema at a molecular level.”Dr. Marie Standl, from Helmholtz Munich, added: “Not every preventive measure works for everyone — and that’s precisely why gene–environment studies are crucial. They help us move toward more personalized, effective prevention strategies.”
However, the study focused on prevention, not treatment. Bringing a dog into a household where a child already has eczema or pet allergies could worsen symptoms. Always speak to your doctor before making changes.
More Than Just Man’s Best Friend
This study highlights how everyday environmental factors, like having a dog, may interact with our genes in unexpected ways. A similar (though less conclusive) protective effect was also seen with older siblings, suggesting more research is needed.Dogs are already cherished for their loyalty and companionship. Now, their presence may extend to disease prevention. As science uncovers more about how genes and lifestyle interact, prevention strategies might one day be as personalized as our DNA — and as simple as a wagging tail.
Reference:
- Gene-Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies - (https://onlinelibrary.wiley.com/doi/10.1111/all.16605)
Source-Medindia