by Dr. Meenakshy Varier on  February 27, 2017 at 11:44 AM Health Watch
  • Chronic stress disrupts sleep, natural fluctuations in body temperature and reduces the diversity of healthy gut bacteria.
  • Prebiotics are dietary fibers that are found naturally in foods which serve as source of food for healthy gut bacteria.
  • Diets rich in prebiotics helps in maintaining a healthy and diverse gut microbiota and normal temperature fluctuations even after stress exposure.

Dietary Prebiotics Help Improve Sleep and Reduce Effect of Stress
Prebiotics can help in improving sleep and reduce the physiological impacts of stress.

Exposure to severe, repeated or chronic stress produces negative health outcomes including disruptions of the sleep/wake cycle, reduction of diversity of healthy gut bacteria and causes temporary flattening of natural fluctuations in body temperature.

The new study by University of Colorado Boulder scientists states that diet rich in prebiotics impact the gut microbiota and may increase gut microbial species that reduce the impact of stress.

"We found that dietary prebiotics can improve non-REM sleep, as well as REM sleep after a stressful event," said Robert Thompson, a post-doctoral researcher in the Department of Integrative Physiology and first author of the new study.

Prebiotics are dietary fibers found naturally in foods like chicory, artichokes, raw garlic, leeks and onions and serve as for good bacteria inside the gut.

Ingestion of the prebiotic fiber by the beneficial gut bacteria helps them to:
  • improve overall gut health
  • release metabolic byproducts
Lead author Monika Fleshner, a professor in the Department of Integrative Physiology explains that these byproducts can influence brain function.


The researchers fed 3-week-old male rats a diet of either standard chow or chow that included prebiotics.

The researchers then monitored the body temperature, gut bacteria and sleep-wake cycles, using EEG, or brain activity testing, of the rats.

The results showed that non-rapid-eye-movement (NREM) sleep was improved in rats on prebiotic diet compared to those on the non-prebiotic diet. The NREM sleep is more restful and restorative.

"Given that sufficient NREM sleep and proper nutrition can impact brain development and function and that sleep problems are common in early life, it is possible that a diet rich in prebiotics started in early life could help improve sleep, support the gut microbiota and promote optimal brain/psychological health," the authors wrote.

The rats on prebiotic diet also had improved rapid-eye-movement (REM) sleep after being exposed to a stressor.

REM sleep is believed to be critical for promoting recovery from stress, with research showing that those who get more REM sleep post-trauma are less likely to suffer from post-traumatic stress disorder. But rats on the prebiotic diet were protected from these impacts, by maintenance of a healthy and diverse gut microbiota and normal temperature fluctuations even after stress exposure.

Fleshner said it's far too early to recommend prebiotic supplements as a sleep aid.

More research is needed to examine the role of prebiotics in promoting sleep, or buffering stress in people.

Though it is early to recommend prebiotic supplements as a sleep aid, researchers suggest loading up on healthy prebiotic fiber from food.

The study is published in the journal Frontiers in Behavioral Neuroscience.


  1. Monika Fleshner et al. Dietary Prebiotics and Bioactive Milk Fractions Improve NREM Sleep, Enhance REM Sleep Rebound and Attenuate the Stress-Induced Decrease in Diurnal Temperature and Gut Microbial Alpha Diversity. Frontiers in Behavioral Neuroscience; (2017)

Source: Medindia

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