is a condition where the valve at
the junction of the left ventricle and the aorta, the largest blood vessel of
the body, is narrowed. This results in a reduction in blood flow to different
parts of the body. In some cases, the condition is present from birth, while in
others; it may be due to conditions like rheumatic fever. Symptomatic cases are
treated with valve replacement.
What is Coronary Heart Disease?
heart disease is a condition that where there is reduced blood supply to a part
of the heart. A severe block in the arteries supplying the heart muscle can
result in a heart attack. Angioplasty is a commonly performed procedure for the
treatment of this condition.
have observed that several patients with severe aortic stenosis also have coronary artery disease
. A study evaluated if
the treatment of both the conditions at the same time is safe and effective.
The study population included 593 patients
who were divided into 3 groups:
I included patients who had aortic stenosis but no coronary artery disease. These
patients underwent only transcatheter aortic valve implantation (TAVI) for the
treatment of the stenosis.
II included patients who had aortic stenosis and coronary artery disease but no
highly significant lesion in the coronary arteries; these individuals were also
treated only with transcatheter aortic valve implantation (TAVI).
III included patients who had aortic stenosis and highly significant coronary
artery lesions; these patients underwent both procedures transcatheter aortic
valve implantation (TAVI) for aortic stenosis and percutaneous coronary
intervention (PCI) for coronary artery disease at the same sitting.
researchers found that the patients in Group III had similar survival up to 3
years as compared to Group I patients. Though the patients in Group III were
exposed to much more contrast dye due to the simultaneous procedures, there was
no increase in kidney damage observed in this group as compared to the others.
researchers thus concluded that doing both the above procedures - transcatheter aortic valve
implantation (TAVI) and percutaneous coronary
intervention (PCI) in patients with severe aortic stenosis and highly
significant coronary artery disease - at the same time is safe and feasible.
- Cardiovascular diseases are the main
cause of death worldwide.
- Over 80% of the deaths due to
cardiovascular disease occur in low or middle-income countries.
artery disease is the most common heart disease in the United States.
Around 720,000 Americans suffer from a heart attack every year.
- About half of Americans have at least
one of the three major risk factors for heart disease, which are high blood
pressure, high LDL cholesterol and smoking.
- In India, cardiovascular diseases are the
largest cause of mortality. There are however regional differences in
cardiovascular mortality, with the mortality being highest in the south Indian,
eastern and north-eastern states and Punjab.