- Insights into mechanism of lowering temperature in specific areas of the brain that could possibly treat epilepsy.
- Focal cooling is a procedure where a device is implanted in a specific part of the brain to reduce electrical signals.
- A rat brain model with epileptic condition was used to study the different mechanisms underlying effects of focal cooling.
Around 50 million people worldwide deal with sudden and recurring seizures
characteristic of epilepsy is caused due to abnormal brain activity and
splurge of electrical signals that result in seizures.
Although there is medications and surgeries available to treat symptoms, the alternative approach of brain cooling may reduce frequency of seizures and may even prevent them. A recent study sheds light on the focal cooling mechanism using computer simulations. The findings are published in Computational Biology.
Brain Cooling Treatment for EpilepsyMost epileptic seizures occur in a limited area called the epileptic focus. Focal cooling is a mechanism where a device is implanted in the epileptic focus or focal area to suppress the abnormal electrical activity in the brain.
Although focal cooling is not a novel idea of treatment, the approach has only been performed successfully in animal models like rodents Although medications are available to treat symptoms of epilepsy, there are up to 35% of patients that cannot effectively control seizures, even with such assistance. The only other alternative for them is surgery, to remove the epileptic focus area of the brain, which can be risky. Focal cooling if approved for clinical use could eliminate the need for surgery altogether.