Chinese health authorities have confirmed that over 11,000 people have been affected and at least four have died from the infectious hand-foot-mouth disease.
During the first quarter of this year, a total of 11,757 cases have been reported in southern Guangxi Zhuang autonomous region, the China Daily reported citing the regional health department.
Hand-foot-mouth disease is a common viral infection that begins in the throat. It is caused by coxsackievirus A16, a member of the enterovirus family.
The disease has also plagued other areas of China.
Hunan province has seen a surge in hand-foot-mouth disease, with over 1,000 cases reported this month, health authorities said.
Also 20 children at a kindergarten in Hong Kong have been infected by the disease.