Porphyromonas gingivalis, the bacterium that is responsible for gum disease also worsens arthritis, say researchers.
University of Louisville School of Dentistry Oral Health and Systemic Diseases group researcher Jan Potempa, PhD, DSc, and an international team of scientists from the European Union's Gums and Joints project found that P. gingivalis produces a unique enzyme, peptidylarginine deiminanse (PAD) which then enhances collagen-induced arthritis (CIA), a form of arthritis similar to RA produced in the lab.
Gingivitis
Gingivitis is a common gum disease caused by poor oral hygiene. It begins with plaque deposition around the gums and teeth.
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PAD changes residues of certain proteins into citrulline, and the body recognizes citullinated proteins as intruders, leading to an immune attack. In RA patients, the subsequent result is chronic inflammation responsible for bone and cartilage destruction within the joints.
The study has been published in PLoS Pathogens.
Source: ANI
Source: ANI
Diet, Nutrition and Supplements for Osteo-Arthritis and Rheumatoid Arthritis
Rheumatoid arthritis patients should consume a diet rich in natural antioxidant and anti-inflammatory nutrients and avoid foods like sugar, saturated fats, and trans fatty acids.
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 Quiz on ArthritisDo you know that there are more than 100 types of arthritis? If you think that only old people suffer from arthritis, take this intriguing quiz to get your facts on arthritis. | Advertisement
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Gum Disease-Causing Bacteria also Induces Protective Protein to Destroy Jaw Bone
The newly-discovered bacterium that leads to gum disease is also responsible for triggering a normally protective protein in the mouth to destroy more bone.
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