The presence of a certain molecule that mimics the structure of estrogen may lead to increased breast tumor growth in patients with high cholesterol levels, a new study has suggested.
"What we have now found is a molecule- not cholesterol itself, but an abundant metabolite of cholesterol - called 27HC, that mimics the hormone estrogen and can independently drive the growth of breast cancer," senior author Donald McDonnell, Ph.D., chair of the Department of Pharmacology and Cancer Biology at Duke, said.
Screening for Breast Cancer with Clinical Breast Examination
Clinical breast examination is a simple and inexpensive method of detecting breast cancer especially in women who do not have access to mammography.
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The research also suggested that dietary changes or therapies to reduce cholesterol may also offer a simple, accessible way to reduce breast cancer risk.
The data also highlights how increased 27HC may reduce the effectiveness of aromatase inhibitors, which are among the most commonly used breast cancer therapeutics.
![Breast Cancer during Pregnancy]( "Breast Cancer during Pregnancy")
Management of breast cancer during pregnancy or pregnancy associated breast cancer requires special consideration to avoid harm to the fetus.
McDonnell said the findings suggested there may be a simple way to reduce the risk of breast cancer by keeping cholesterol in check, either with statins or a healthy diet.
Additionally, for women who have breast cancer and high cholesterol, taking statins may delay or prevent resistance to endocrine therapies such as tamoxifen or aromatase inhibitors.
The study is published in the journal Science.
Source: ANI
Breast Cancer during Pregnancy
Management of breast cancer during pregnancy or pregnancy associated breast cancer requires special consideration to avoid harm to the fetus.
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McDonnell said the findings suggested there may be a simple way to reduce the risk of breast cancer by keeping cholesterol in check, either with statins or a healthy diet.
Additionally, for women who have breast cancer and high cholesterol, taking statins may delay or prevent resistance to endocrine therapies such as tamoxifen or aromatase inhibitors.
The study is published in the journal Science.
Source: ANI
Breast Cancer Screening using Mammogram
Breast cancer if detected early can be completely cured. Mammography is used to screen women for breast cancer.
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 Breast Cancer - Prevention and Management with Lifestyle ChangesLifestyle choices may or may not cause breast cancer but healthy lifestyle changes can open up avenues beyond breast cancer. Good habits will allow one to fight breast cancer and to live with dignity. | Advertisement
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