Gene Expression Linked to Bipolar Disorder Discovered
Differences in gene expression were identified in two specific regions of the brains of hundreds of patients who had bipolar disorder.
Differences in gene expression were identified in two specific regions of the brains of hundreds of patients who had bipolar disorder.
‘New genomic technology helps simultaneously analyze various genetic materials — DNA, RNA, and chromatin (combination of DNA and protein).
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“These diseases can broadly affect many cell types. But there could be certain cell populations that are particularly vulnerable. Genetic research has pinpointed the regions of the genome that are relevant for diseases like Alzheimer’s. We’re providing another data dimension and identifying the cell types affected by these genomic regions,” says co-first author Chongyuan Luo, assistant professor of human genetics at the David Geffen School of Medicine at UCLA. “This multimodal platform is going to be useful by providing a comprehensive database that can be used by the groups trying to integrate their single-modality data. This new information can also inform and guide future cell-type classification,” says Joseph Ecker, director of the Genomic Analysis Laboratory at Salk, the Salk International Council Chair in Genetics and Howard Hughes Medical Institute Investigator.
Source-Medindia
Neurodegenerative Diseases and Their Link!
Common thread between several neurodegenerative diseases has been finally discovered by a new study.
Common thread between several neurodegenerative diseases has been finally discovered by a new study.
Single Test can Detect Over 50 Genetic Diseases
Single DNA test can give a clear genetic diagnosis. This helps patients avoid years of unnecessary muscle or nerve biopsies for genetic diseases.
Single DNA test can give a clear genetic diagnosis. This helps patients avoid years of unnecessary muscle or nerve biopsies for genetic diseases.
