Genetic Therapy Heals Damage Caused by Heart Attack: Study

by Colleen Fleiss on  May 10, 2019 at 8:20 AM Heart Disease News
RSS Email Print This Page Comment bookmark
Font : A-A+

Gene therapy that can induce heart cells to regenerate after a heart attack has been developed by researchers from King's College London.
Genetic Therapy Heals Damage Caused by Heart Attack: Study
Genetic Therapy Heals Damage Caused by Heart Attack: Study

Myocardial infarction, more commonly known as a heart attack, caused by the sudden blocking of one of the cardiac coronary arteries, is the main cause of heart failure, a condition that now affects over 23 million population in the world, according to the World Health Organisation. At present, when a patient survives a heart attack, they are left with permanent structural damage to their heart through the formation of a scar, which can lead to heart failure in the future. In contrast to fish and salamander, which can regenerate the heart throughout life.

In this study, published today in Nature, the team of investigators delivered a small piece of genetic material, called microRNA-199, to the heart of pigs, after a myocardial infarction which resulted in the almost complete recovery of cardiac function at one month later.

Lead author Professor Mauro Giacca, from King's College London said: "It is a very exciting moment for the field. After so many unsuccessful attempts at regenerating the heart using stem cells, which all have failed so far, for the first time we see real cardiac repair in a large animal."

"It will take some time before we can proceed to clinical trials" explained Professor Giacca. "We still need to learn how to administer the RNA as a synthetic molecule in large animals and then in patients, but we already know this works well in mice".

Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Advertisement

Recommended Reading

More News on:

Genetics and Stem Cells Reiki and Pranic Healing Heart Healthy Heart Statins Mitral Valve Prolapse Aortic Valve Stenosis Christianson Syndrome Pericarditis 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive