About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Genetic Profile Between Schizophrenia, Bipolar Disorder Unveiled

by VR Sreeraman on July 20, 2008 at 1:01 PM
Font : A-A+

 Genetic Profile Between Schizophrenia, Bipolar Disorder Unveiled

Researchers at the University of California, Irvine have found 78 genes that show a similar pattern of abnormal regulation in the brains of people suffering from schizophrenia and those with bipolar disorder.

"The pattern of dysregulation was similar in the prefrontal cortex for both illnesses and pointed to key processes. Part of the set of core genes could be explained by medication responses; however most of these core genes did not appear to be correlated to medication response," said Dr. Ling Shao of the university's School of Medicine, who conducted the research with his colleague Marquis Vawter.

Advertisement

The researchers have reported their findings in the journal Biological Psychiatry.

Dr. John H. Krystal, Editor of Biological Psychiatry, says: "The new findings by Drs. Shao and Vawter provide evidence that there are a large number of genes that show a similar pattern of abnormal regulation in their sample of post-mortem brain tissue from individuals who had been diagnosed with schizophrenia or bipolar disorder. This overlap could provide insight into the neurobiology of both disorders."
Advertisement

The researchers believe that understanding of the neurobiology related to the shared genes may lead to the discovery of common brain mechanisms that may guide the identification of new and more effective treatments.

In their study report, the researchers also refer to recent discussions that have focused on considering schizophrenia and bipolar disorder as a single illness viewed along a continuum of mood and psychotic symptoms.

"We have traditionally treated these diagnoses as unrelated conditions even though many of the same medications, such as antipsychotic medications, are used to treat both conditions," notes Dr. Krystal.

Source: ANI
SRM
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
Long-Term Glycemic Control - A Better Measure of COVID-19 Severity
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Schizophrenia Genetics and Stem Cells Bipolar Disorder Christianson Syndrome Loss of Taste Schizoaffective Disorder Euphoria Social Anxiety Disorder Anosognosia Mood Swings 

Recommended Reading
Schizophrenia
Schizophrenia is a mental disorder characterized by symptoms of thought, behavior and social ......
Scientists Discover Protein Biomarker for Schizophrenia Risk
Neuroscientists at the UK-based University of Cambridge say that a protein found in immune cells ......
Majority of Psychiatric Patients Suffer from More Than One Disorders
Researchers at the Rhode Island Hospital have found that most psychiatric patients have more than .....
Anosognosia
Anosognosia is the lack of awareness or insight in a patient to understand that he/she has a disease...
Bipolar Disorder
Bipolar Disorder is a brain disorder in which people show “mood swings”. Changes in the level of ne...
Christianson Syndrome
Christianson syndrome is a condition that occurs due to mutations (abnormal changes) in the gene SLC...
Euphoria
Euphoria is an exaggerated state of happiness and well-being that is beyond the normal emotional res...
Loss of Taste
Symptom of loss of taste usually occurs in combination with loss of smell and can be complete loss o...
Mood Swings
It is normal to go through mood changes such as joy, sadness or anger every day, but when these mood...
Schizoaffective Disorder
Schizoaffective disorder is a serious mental disorder in which the individual reflects symptoms that...
Social Anxiety Disorder
Social anxiety disorder is a common mental health problem where a person is abnormally fearful of so...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use