Huntington's disease is an autosomal-dominant inherited neurodegenerative disease with a distinct phenotype. But the pathogenesis is very much unclear.
Origin of Huntington's Disease in the Brain Traced Down by UCLA Scientists
The gene mutation that causes Huntington's disease kills only two types of brain cells, though it appears in every cell in the body.
The gene mutation that causes Huntington's disease kills only two types of brain cells, though it appears in every cell in the body.
Their findings, published in the Neural Regeneration Research (Vol. 9, No. 4, 2014), suggest that clinical diagnosis of Huntington's disease requires a combination of clinical symptoms, radiological changes, and genetic diagnosis.
Source-Eurekalert
New Drug Targets for Treating Huntington's Disease
Improved walking and prolonged survival seen in a mouse model of Huntington's disease by tweaking a specific cell type's ability to absorb potassium in the brain, reports study published by UCLA.
Improved walking and prolonged survival seen in a mouse model of Huntington's disease by tweaking a specific cell type's ability to absorb potassium in the brain, reports study published by UCLA.
Amino Acid Deficiency Causes Brain Degeneration in Huntington's Disease
The loss of the ability to make the amino acid cysteine may be the cause of vast disintegration of a part of the brain called the corpus striatum.
The loss of the ability to make the amino acid cysteine may be the cause of vast disintegration of a part of the brain called the corpus striatum.
Huntington Proteins and Their Nasty Interactions
Thousands of protein interactions involving huntingtin, the protein responsible for Huntington's disease, have been identified and categorized by researchers at the Buck Institute.
Thousands of protein interactions involving huntingtin, the protein responsible for Huntington's disease, have been identified and categorized by researchers at the Buck Institute.
