About Careers MedBlog Contact us

Genetic Analysis Reveals What Makes Us Look Old

by VR Sreeraman on July 4, 2009 at 11:55 AM
Font : A-A+

 Genetic Analysis Reveals What Makes Us Look Old

A genetic analysis of human skin has revealed what makes us look old, say American scientists.

According to scientists, the finding could throw up ways to smooth away wrinkles and provide a quantifiable way to test claims made for skin products, reports New Scientist.


Rosemary Osborne of Procter and Gamble in Cincinnati, Ohio, and colleagues used DNA microarrays, common in the drugs industry, to measure the expression of thousands of genes in skin of different ages.

The researchers compared gene expression in skin samples from the buttocks and forearms of 10 young and 10 older women.

In older skin, they found a decrease in the expression of genes involved in cholesterol and fatty acid synthesis.

The researchers also found that the opposite was true for genes associated with inflammation and other components of the immune system, suggesting that the immune system may play a role in aging.

Treating the older skin with niacinamide, which helps skin retain moisture, damped down expression of genes related to inflammation.

The researchers say that targeting this inflammation might one day help to keep wrinkles at bay.

The findings appear in the Journal of Drugs in Dermatology.

Source: ANI

Recommended Reading

This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Genetic Analysis Reveals What Makes Us Look Old Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests