Medindia
Advertisement

First Large-Scale Ebola Vaccine Tests to Begin in Guinea on March 7

by Bidita Debnath on March 5, 2015 at 10:48 PM
Font : A-A+

 First Large-Scale Ebola Vaccine Tests to Begin in Guinea on March 7

The first large-scale trial of an Ebola vaccine will begin in Guinea at the weekend, said the World Health Organization, weeks after a similar test kicked off in neighbouring Liberia.

The Phase III testing of the vaccine -- one of two that are in the most advanced stages of development -- aims to ensure it provides protection against the virus that has killed some 9,800 people in Liberia, Guinea and Sierra Leone.

Advertisement

There is no licensed treatment or vaccine for Ebola, and the WHO has endorsed rushing potential ones through trials in a bid to stem the epidemic.

Researchers have said that it remains unknown what level of immune response is needed to protect humans from Ebola, which causes often fatal haemorrhaging, organ failure and severe diarrhoea.
Advertisement

"If a vaccine is found (to be) effective, it will be the first preventive tool against Ebola in history," WHO chief Margaret Chan said in a statement.

The two candidate vaccines currently being developed -- CAd3 by Britain's GlaxoSmithKline and VSV-EBOV by Merck and NewLink Genetics -- have both passed safety tests on humans.

They are already being tested in Liberia, and the trial of VSV-EBOV will kick off in Guinea on March 7, WHO said.

Vaccinations will take place in areas of Basse Guinee, the region that currently has the highest number of cases in the country, it added.

Authorities will use a so-called "ring vaccination" approach that was used to eradicate smallpox in the 1970s, tracking down anyone who could have been exposed to a newly diagnosed patient and vaccinating them if they agree.

Part of the contacts will be vaccinated immediately after the new case is detected, while others will be given a shot three weeks later -- the length of the virus's incubation period.

"The Ebola epidemic shows signs of receding," said Marie-Paule Kieny, who leads the Ebola research and development effort at WHO.

In worst-hit Liberia, for instance, no new confirmed cases have been reported for a full week, WHO said, a first since May.

"But we cannot let down our guard until we reach zero cases," Kieny said in the statement.

"An effective vaccine to control current flare-ups could be the game-changer to finally end this epidemic and an insurance policy for any future ones."

Source: AFP
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Sedentary Behavior Precipitates Night-Time Hot Flashes
Gonorrhea
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Congo Fever Vaccination for Children Ebola Virus Disease Top 10 Vaccine Myths Debunked 

Recommended Reading
Researchers Warn Against Complacency on Ebola Vaccines
A team of international scientists called for new Ebola vaccines to be made available in months ......
Ebola Vaccine Trials Halted Due to Fall in New Ebola Cases
The clinical trials for a new Ebola vaccine in Liberia were halted due to a fall in new cases, ......
Large-Scale Trials of Two Ebola Vaccines Begins in Liberia
The first large-scale trials of two Ebola vaccines, GlaxoSmithKline's Chad3-EBO-Z and Merck and ......
Ebola Vaccine Considered to be Safe
The experimental Ebola vaccine has been found to be safe in preliminary results from a clinical ......
Congo Fever
Crimean-Congo Hemorrhagic fever (CCHF) is a viral disease that affects people who are bitten by infe...
Ebola Virus Disease
Ebola is caused by a virus via direct contact with body fluids or infected blood. Scientists have id...
Top 10 Vaccine Myths Debunked
Childhood vaccination has saved many lives, yet lots more has to be done to increase awareness and e...
Vaccination for Children
Vaccines are biological products that impart immunity to the recipient. Vaccines may be live attenua...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use