Alzheimers drug human trial:26-week human trial, which will include 90 patients mild to moderate Alzheimers,potentially cure disease affecting 50 million people

‘Alzheimer’s drug human trial: The 26-week human trial, which will include 90 patients with mild to moderate Alzheimer's, could potentially lead to a "cure" for the disease affecting nearly 50 million people worldwide.’

The drug, known as ORY-2001, contains a small molecule which inhibits two enzymes in the brain, LSD1, and MAOB, which are responsible for promoting DNA damage and inhibiting repair. 




By blocking their action, the new drug repairs and prevents further damage.
The drug also stops inflammation in the brain, a key factor perhaps causing mental decline, the report said.
"Curing Alzheimer's is now on the horizon. The mechanism of this drug may lead to treatments that protect genetic material from the influences of ageing," Stuart Ratcliffe, chief scientific officer at St Pancras Clinical Research in London, was quoted as saying.
"I believe this is ground-breaking. Neuro-degenerative diseases are a massive problem so heading these off is a holy grail of medicine," Ratcliffe added.
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"Alzheimer's is our biggest killer and is spiralling," Ratcliffe said.
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Source-IANS