Compound formed during fermentation of beer, wine has potential to prevent organophosphate-triggered seizures from developing into epilepsy, revealed new research published in eNeuro.
Left untreated, organophosphate poisoning can lead to severe breathing and heart complications. It is also known to cause seizures. Some patients are resistant to treatment with the anti-anxiety drug diazepam, the first line of defense for such poisoning, and its effectiveness decreases the longer the seizure lasts.
Asheebo Rojas and colleagues compared the ability of two treatments -- diazepam and the anesthetic urethane (ethyl carbamate), commonly formed in trace amounts during fermentation of beer and wine from the reaction of urea and ethanol -- to interrupt seizures in rats exposed to the organophosphate diisopropyl fluorophosphate.