About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Fefferson Doctors Take Their Case for High-Dose Radiotherapy Technique After Radical Prostatectomy Further

by Tanya Thomas on April 17, 2011 at 4:27 AM
Font : A-A+

 Fefferson Doctors Take Their Case for High-Dose Radiotherapy Technique After Radical Prostatectomy Further

A widely-available yet expensive radiotherapy technique used to treat prostate cancer patients after surgery has promising benefits—higher dose and less damage to the rectum and bladder—compared to a less precise technique, Thomas Jefferson University researchers document for the first time in a new study published in Practical Radiation Oncology.

A team of radiation oncologists and medical physicists, including lead author Amy Harrison, M.S., the medical physics clinical supervisor at Jefferson, show that intensity-modulated radiotherapy (IMRT) allows a higher dose to be delivered to the area after their glands have been removed while maintaining the same dose to the rectum and bladder compared to 3D conformal radiation therapy.

Advertisement

Higher doses to the prostate bed have been shown to be more effective in that setting for controlling prostate-specific antigen (PSA) levels.

IMRT is currently being used at some centers in the United States, including the Kimmel Cancer Center, to treat men after they've had their prostate glands removed, but detailed data are limited evaluating the advantages of this approach compared to 3D conformal radiation therapy. In other words, documented justification for the approach was lacking.
Advertisement

"This is the first contemporary study to look at IMRT versus 3D radiation therapy for post-op patients using consensus guidelines," said Timothy Showalter, M.D., assistant professor of Radiation Oncology at Thomas Jefferson University, and an expert in image-guided therapy of prostate cancer. "This is also filling a gap for information that no one supplied before to show that this radiotherapy is beneficial in the postoperative setting, similar to its role in non-surgical approaches."

"The reason that it's more and more relevant now is that there are emerging data to support doing adjuvant radiation therapy after prostatectomy for high risk patients," he added.

There a variety of toxicities associated with radiation therapy after a prostatectomy, including late gastrointestinal bleeds, loose stools and painful bowel moments, but IMRT can minimize damage that can lead to such side effects.

"The biggest benefit for our patients who have a PSA failure after radical prostatectomy is to be able to deliver high dose radiation while sparing normal tissue," said Dr. Showalter.

Future studies, the researchers report, should determine whether these advantages translate into improved clinical outcomes for prostate cancer patients.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
World Heart Day in 2022- Use Heart for Every Heart
Anemia among Indian Women and Children Remains a Cause of Concern- National Family Health Survey-5
H1N1 Influenza Prevention in Children: What Parents Need to Know
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Benign Prostatic Hyperplasia Radiotherapy Hodgkins Lymphoma Non-Hodgkins Lymphoma Rhabdomyosarcoma Different Medical Specialists and their Area of Medical Expertise Male Breast Cancer External Beam Radiation Therapy for Prostate Cancer Radical Prostatectomy Radiosurgery 

Most Popular on Medindia

The Essence of Yoga Noscaphene (Noscapine) Hearing Loss Calculator Turmeric Powder - Health Benefits, Uses & Side Effects A-Z Drug Brands in India Blood Pressure Calculator Sanatogen Post-Nasal Drip Drug Interaction Checker Daily Calorie Requirements
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Fefferson Doctors Take Their Case for High-Dose Radiotherapy Technique After Radical Prostatectomy Further Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests