AML is a rapidly progressing cancer that crowds out normal cells in the bone marrow and bloodstream, resulting in low numbers of normal blood cells and a continuous need for transfusions, reports Xinhua news agency.
"Approximately 25 to 30 per cent of patients with AML have a mutation in the FLT3 gene. These mutations are associated with a particularly aggressive form of the disease and a higher risk of relapse," Richard Pazdur, acting director of the Office of Haematology and Oncology Products in the FDA's Centre for Drug Evaluation and Research, said on Wednesday.
The efficiency of Xospata was studied in a clinical trial of 138 patients with relapsed or refractory AML having a confirmed FLT3 mutation.
Twenty-one per cent of patients achieved complete remission or complete remission with partial haematologic recovery with treatment, according to FDA.
Of the 106 patients who required red blood cell or platelet transfusions at the start of treatment with Xospata, 31 per cent became transfusion-free for at least 56 days, according to the FDA.
- » News Central
- » Popular News
- » Latest Health News
- » News Category A-Z (500+)
- » Health News and Press Release
- » News Archive
- » News Photo Gallery
- » Lifestyle and Wellness
- » Health Watch
- » Health In Focus
- » Celebrating Life
- » Breaking Health News
- » News From Other Resources
- » India Special
- » News Video Gallery
- » Medindia Exclusive - Interviews and In depth Reports