Exposure to Fetal Nicotine Harms Breathing

by Colleen Fleiss on  November 12, 2019 at 12:10 AM Child Health News
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Nicotine exposure during development inhibits the function of neurons controlling the tongue, found research published in eNeuro. This impairment may be a factor in sudden infant death syndrome in humans.
Exposure to Fetal Nicotine Harms Breathing
Exposure to Fetal Nicotine Harms Breathing

The hypoglossal nerve activates the muscles of the tongue. Wollman et al. exposed rats to nicotine in the womb and during the first few days of life. The team then measured the electrical activity of hypoglossal neurons during normal breathing and when breathing is stressed.

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Normally, when breathing is obstructed, such as a blocking an animal's nostrils, a flood of excitatory neurotransmitters activate the hypoglossal neurons to move the tongue and open the airway. At rest, hypoglossal neurons in the rats exposed to nicotine behaved normally.

However, during the breathing stressor test, the neurons from nicotine-exposed rats did not respond as robustly as those in the control rats, leading to difficulty breathing.

Source: Eurekalert

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