About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Exposure to Certain Bacteria may Protect Toddlers from Wheezing and Allergic Reactions

by Dr. Enozia Vakil on June 7, 2014 at 7:41 PM
Font : A-A+

 Exposure to Certain Bacteria may Protect Toddlers from Wheezing and Allergic Reactions

Exposure to certain combination of allergens and bacteria within the first year of life may protect the child from wheezing and other allergic diseases, a new research has found. These observations come from the Urban Environment and Childhood Asthma (URECA) study, which aims to identify factors responsible for asthma development in children from inner-city settings, where the disease is more prevalent and severe.

Since 2005, the URECA study has enrolled 560 children from four citiesóBaltimore, Boston, New York and St. Louis. The children all have at least one parent with asthma or allergies, placing them at high risk for developing asthma. The study is following the children from birth, and the current publication evaluates the group through three years of age. During early life, recurrent wheezing and sensitivity to common allergens are risk factors for developing asthma.

Advertisement

In the current study, the researchers measured the frequency of wheezing episodes and levels of exposure to five common inner-city allergensócat, cockroach, dog, dust mite and mouse. Surprisingly, they found that exposure to cockroach, mouse and cat during the first year of life was associated with a lower risk of recurrent wheezing by age three. A smaller study within the URECA cohort tested whether bacteria, measured in house dust, influence asthma risk.

Researchers sorted 104 children into four groups: no wheezing or sensitivity to allergens, wheezing only, sensitivity to allergens only, or both wheezing and sensitivity to allergens. They found that children with no wheezing or sensitivity to allergens at age three were more likely to have encountered high levels of allergens and a greater variety of bacteria, particularly those belonging to the Bacteriodes and Firmicutes groups, during their first year of life.
Advertisement

These observations support the emerging concept that early-life exposure to high bacterial diversity may protect kids from developing allergies. Most importantly, the findings show that this protection is even stronger when children also encounter high allergen levels during this time. The URECA study, funded by NIH's National Institute of Allergy and Infectious Diseases through its Inner-City Asthma Consortium, is no longer recruiting.

Additional funding was provided by the NIH's National Center for Advancing Translational Sciences. The research was conducted by investigators from several institutions, including the University of Wisconsin-Madison; the University of California, San Francisco; and Johns Hopkins University.



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Breast Cancer Awareness Month 2021 - It's time to RISE
First-Ever Successful Pig-To-Human Kidney Transplantation
World Osteoporosis Day 2021 -
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Acute Bronchitis Allergy Asthma Shigellosis MRSA - The Super Bug Dealing with Pollen Allergy Food Safety for Health Wheezing Antibiotics Asthma in Children and Adults 

Recommended Reading
Toddler Constipation
Toddler constipation is non-passage of stool/ motion by child for 4 days or more. Toddler ......
Acute Bronchitis
Acute bronchitis is a short term inflammation of the bronchi of lungs. It is usually caused by a ......
Allergy
An allergy is a hypersensitive disorder of immune system. Substances that often cause allergic react...
Antibiotics
Antibiotics are among the most used and abused medications. This article explains some general featu...
Asthma
It's a lung condition characterized by inflammation of the bronchi and constriction of the airways t...
Asthma in Children and Adults
Adult and childhood asthma are caused due to inflammation of the airways, but differences exist in t...
Dealing with Pollen Allergy
The plants around you that give you sniffles in your nose at specific time of the year are the sourc...
MRSA - The Super Bug
MRSA infection is the most dreaded hospital or community acquired infection that can become ......
Shigellosis
Shigellosis or Bacillary Dysentery is a common cause of gastro-enteritis worldwide and can cause blo...
Wheezing
Wheezing is a sound arising from the airways due to an obstruction or narrowing, which prevents the ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use