In the experiments, volunteers are instructed to immediately look away from a small light that randomly appears on a screen in front of them. This "anti-saccade" test shows if the brain is able to engage the planning centers of the prefrontal cortex to overcome the impulse to look toward the light rather than away from it. Dr. Luna's team has found in previous studies that children succeed in about half their tries, teens in about 70 percent of tries and adults in about 90 percent of tries. People with mental illnesses typically struggle with the task.

The study team had volunteers do the same tasks while scanning their brains with functional MRI. They found that much of the architecture of mature brain is in place by adolescence, but the ability of the networks to talk to one another and integrate information is still a work in progress.

"Further enhancement of this network integration is likely why adults can switch and very quickly adapt their behavior to changing circumstances, which is more difficult for adolescents," Dr. Luna explained.

She added that while parents and teachers sometimes find bewildering the choices teens might make, their brains are perfectly adapted to explore and take some chances as they become independent adults.

"Across societies and species, we know that adolescence is a period of increased sensation seeking that can lead to risk taking, which increases mortality rate," Dr. Luna said. "Also, we often see during this period the first signs of mental illnesses such as schizophrenia, depression and eating disorders. All of these have a neurobiological basis, so if we know how the brain is changing, we might be able to figure out a way to intervene earlier in life."

Dr. Luna and researchers from the Children's National Medical Center, Washington, D.C.; Columbia University Medical Center; and University of California, Berkeley, will present their work from 1:30 to 4:30 p.m., Saturday, Feb. 14, during a AAAS session called "From Womb to Tomb."



Source: Medindia