Age-related macular degeneration (AMD) leading to vision loss is linked with increasing girth in men, report researchers at the University of Melbourne.
The researchers tracked changes in the waistlines of more than 21,000 men and women, aged between 40 and 69, over several years and observed how many developed AMD later on. They found that abdominal fat releases the female hormone oestrogen into the body. Using animals in their studies they discovered that the hormone can cause inflammation in blood vessels at the back of the eyes. This is why women, having had higher levels of oestrogen throughout their lives, are not similarly affected.
'There is evidence that chronic inflammation is involved in AMD and obesity is a pro-inflammatory state,' said the scientists.
Most develop 'dry AMD', which develops over several years. 'Wet AMD', which can cause blindness in just three months, happens when new blood vessels develop over the macula in the eye and then start to leak fluid, causing scar tissue to form and destroying vision in the centre of the eye. This makes it difficult to recognize faces, read or watch TV.
Diet is a crucial factor in minimizing the risk of AMD. Eating red meat raised the risk by half, while eating chicken cut down the risk by half. Eating more fruit, vegetables and nuts cuts down the disease rates by 20 per cent.
Right now, men in Britain need to be concerned about reducing their waistlines to minimize the risk of AMD.