Exercise can help improve both memory and mood after whole-brain radiation treatment, that's the conclusion of a new study in rodents. The study has been presented by Duke University scientists at the Society for Neuroscience meeting. "This is the first demonstration that exercise can prevent a decline in memory after whole-brain radiation treatment," said lead researcher and graduate student Sarah Wong-Goodrich of the Duke Department of Psychology and Neuroscience. Whole-brain radiation is sometimes used to treat brain cancers in humans. In the experiment, one group of mice that had brain radiation stayed in their cages under normal conditions, living with other mice, eating and playing as they liked. But a different group of mice that had radiation were given daily access to a cage with a running wheel, which they could use if they wanted to. The animals were tested for how well they remembered spatial features in their environment for locating a preferred escape hole to exit a well-lit maze and hide. The mice completed tests at the two-week and the three-month mark after their irradiation to get a baseline and then to see how they fared over time. Mice that had radiation plus access to running did as well at remembering where the hole was as normal mice that didn't exercise. Irradiated mice that had no access to an exercise wheel eventually showed no particular preference for the section of the maze with the escape hole. "It was remarkable that the irradiated, running mice were just like the normal, non-irradiated mice that didn't exercise. We were expecting some memory retention issues with a longer delay and there weren't any," said Wong-Goodrich. Wong-Goodrich said that exercise appears to actually protect against the loss of memory and the increase in depressive-like behaviors. The mice also were tested for depressive-like behavior, using gentle restraints, which they worked to escape from. Two weeks after radiation, the irradiated mice gave up sooner than the normal mice. Three months after radiation, the runners that had brain radiation, however, tried just as hard as the normal mice, while their non-running counterparts gave up more readily. Radiation knocks out the ability of the brain to produce new nerve cells, called neurons. Williams said that they were able to measure increases in certain growth factors in the exercising mice that might be necessary to help cells divide. Wong-Goodrich said that exercise might help by increasing blood flow to the hippocampus area of the brain, which is an important structure for learning, memory, and spatial navigation.Source: ANILIN << Bollywood Movies Inspire Indian Weddings Imphal Pharmacists' Protest Against Monetary Demands by Mil... >> Recommended Reading Brain Tumor - Treatment Treatment for brain tumor depends upon the patient age, stage of the disease, type and location. Surgery, craniotomy, radiation and chemotherapy are used to treat brain cancer. READ MORE Top Ten Facts About Brain Tumors Quick valuable reference that enlists interesting facts about brain tumors. READ MORE Exercise can Help Repair Brain Cells of Children After Radiation Therapy Exercise can help repair of brain cells of children after radiation therapy. READ MORE Computerized Brain Exercises can Improve Memory in Elderly In a novel study, Mayo Clinic researchers have found that computerized brain exercises can help boost memory power in older adults. READ MORE Exercise and Fitness Exercise is about revamping your lifestyle, not just weight loss. Exercise to get healthy – that way, you’ll last longer at it and get better results. READ MORE Lifestyle Modification: No Big Deal! Simple and practically possible lifestyle changes can make a huge difference in improving our health status without actually putting much effort. READ MORE Parkinsons Disease Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. Symptoms of Parkinson’s disease are correctable to an extent. READ MORE Radiotherapy A detailed account of radiation, its mode of action, side effects and dosage in the treatment of cancer. READ MORE Tips to Live Longer Though life is temporary and short, it is possible to maximize the span of our existence by living healthy and savoring every moment of life, read our tips to live longer READ MORE X-Ray Encyclopedia section of medindia gives a brief Overview of X-Ray READ MORE Most Popular on Medindia Find a Doctor Drug - Food Interactions Calculate Ideal Weight for Infants More News on: Parkinsons DiseaseRadiotherapyX-RayParkinsons Disease Surgical TreatmentDiet Lifestyle and Heart DiseaseTips to Live LongerBrainBrain FactsExercise and FitnessLifestyle Modification: No Big Deal!