Functioning of thyroid hormones has a strong association with the risk of atrial fibrillation (AF), reveal scientists at Vanderbilt University Medical Center. AF is an irregular heart rhythm which increases the risk of heart-related complications and stroke. The phenome-wide association study scanned the medical records of more than 37,000 people for an association between genetically determined variation in thyroid stimulating hormone levels (a measure of thyroid function) and AF risk. Previous observational studies have found that subclinical hyperthyroidism, an overactive thyroid which does not meet the clinical threshold for diagnosis or treatment, nevertheless can increase the risk of AF. But whether to treat subclinical hypo- or hyperthyroidism to reduce AF risk remains a matter of debate in the medical community. ‘Patients with genetically-determined variations in thyroid hormones, despite having physiologically accepted ‘normal’ range are more susceptible to AF risk.’ The current study, published today in the journal JAMA Cardiology, found that genetically determined variations in thyroid function, even those which fall within a physiologically accepted "normal" range, still can increase the risk for AF. The decision to treat subclinical thyroid disease should account for this new evidence, as "antithyroid medications to treat hyperthyroidism may reduce AF risk (while) thyroid hormone replacement for hypothyroidism (low thyroid function) may increase AF risk," the researchers concluded. Source: Eurekalert << Teamwork, High-tech Tools Separated Delaney Twins Joined at ... Blood Pressure Above Normal in Young Adults Linked to Brain ... >> Recommended Reading Atrial Fibrillation Atrial fibrillation may not be life-threatening in itself but it is important to understand the causes, symptoms and treatments because of the risk of life-threatening complications. READ MORE Drugs for Atrial Fibrillation Atrial fibrillation is a condition with irregular heart rhythm. Be aware of the prescribed drugs, their side effects and precautions, to avoid risk to life. READ MORE Cardiac Pacemaker for Abnormal Heart Rhythms A pacemaker stimulates the heart with electrical signals when it detects arrhythmias of the heart. Pacemakers are classified based on the number of lead electrodes used and the type of pacing involved. READ MORE Hyperthyroidism Hyperthyroidism is a condition in which the thyroid gland makes excessive thyroid hormone. Grave's disease is the most common cause of hyperthyroidism. READ MORE Can Drugs Affect Thyroid Function? Some medications affect the normal function of thyroid gland leading to thyroid function disorders in the form of hypothyroidism or hyperthyroidism. Read Patient Information Leaflet of medications to be aware of such effects and conduct regular monitoring of thyroid function to avoid complications READ MORE Hashimoto´s Thyroiditis Hashimoto’s thyroiditis is an autoimmune disorder of the thyroid causing hypothyroidism. Synthetic hormone levothyroxine is an effective lifelong oral drug. READ MORE Hypothyroidism Symptoms of hypothyroidism are often general, unspecific changes in the body. Lethargy, weight gain, stiffness and cramping of muscles are some of the symptoms of hypothyroidism. READ MORE Hypothyroidism during Pregnancy Hypothyroidism is a health condition where the thyroid gland produces less thyroid hormone. Hypothyroidism during pregnancy can seriously impact the health of the mother and baby in the womb. READ MORE Iodine Deficiency Disorder To control IDD, the ‘National Goiter Control Program (NGCP)’ was launched which was later renamed as the ‘National Iodine Deficiency Disorder Control Program (NIDDCP)’. READ MORE Thyroid Cancer “Shaped like a butterfly she sits within the neck,” that’s what an anonymous poet wrote about the thyroid gland but it can become cancerous and spread to other parts. READ MORE Most Popular on Medindia Turmeric Powder - Health Benefits, Uses & Side Effects Selfie Addiction Calculator Loram (2 mg) (Lorazepam) More News on: Iodine Deficiency DisorderHyperthyroidismHypothyroidismThyroid CancerHashimoto´s ThyroiditisHypothyroidism during PregnancyCan Drugs Affect Thyroid Function?