About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Epilepsy Drug Helps Alcoholics to Overcome Insomnia, Cravings

by VR Sreeraman on August 5, 2008 at 3:46 PM
Font : A-A+

 Epilepsy Drug Helps Alcoholics to Overcome Insomnia, Cravings

University of Michigan researchers have found that an epilepsy drug might reduce insomnia, and help alcoholics become sober again.

Alcoholics are highly likely to suffer from chronic insomnia that keeps them from getting enough night sleep, and the condition reduces of recovering from alcohol dependence.

Advertisement

The researchers have found that epilepsy drug, gabapentin, can reduce insomnia in recovering alcoholics, and help them stay away from alcohol more successfully.

The team conducted a randomised, placebo-controlled trial on 21 insomniacs, and found that 30 percent of the patients who received gabapentin during alcohol recovery relapsed to drinking, compared with 80 percent of those who received a placebo.
Advertisement

"We showed that the patients who got the real drug, rather than placebo, were less likely to relapse to drinking -- or if they relapsed it was later," said lead author Dr Kirk Brower, FASAM, the executive director of U-M Addiction Treatment Services and a professor of psychiatry at the U-M Medical School.

"In other words, gabapentin prevented and delayed relapse. Meanwhile, patients reported sleeping better in both the treatment and placebo groups, which may be due to the gabapentin in the first group and the resumption of drinking in the other," he added.

Co-author Dr. Flavia Consens, an associate professor of neurology and member of the U-M Sleep Disorders Centre said that as many as 70 percent of people with alcohol problems suffer insomnia, while others cope with other sleep disturbances including breathing problems known as sleep apnea.

"There may be some underlying chemical changes in the brain that prompt alcoholics to report more insomnia as a co-existing condition than non-alcoholics," she said.

"A possible explanation of these new findings is that the gabapentin might decrease the insomnia initially, and the patient may not need or crave alcohol as a treatment for the insomnia.

"We're also looking into other factors that may have an effect on the neurochemistry of the brain, and see how they could impact recovery and sleep," she added.

Brower notes that the medication dose and schedule used in the study may have contributed to the relatively weak effect on sleep that was seen from gabapentin.

Patients took one dose each evening, rather than the three doses throughout the day that are routinely given for epilepsy or pain.

The study is published in the August issue of the journal Alcoholism: Clinical and Experimental Research.

Source: ANI
SRM
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Toxicity Epilepsy Febrile Fits / Febrile Convulsions Signature Drug Toxicity Stress Relief Through Alternative Medicine Pancreatitis Melatonin Reye’s Syndrome Convulsions Electroencephalogram 

Recommended Reading
Alcohol abuse
Alcohol abuse...
Blood Alcohol Level
Use this calculator to estimate your blood alcohol content and the permissible limit in different .....
Insomnia
Difficulty in initiating and maintaining sleep is known as insomnia. It is a symptom that occurs ......
Sleep Disturbances In Women
The physical, emotional and hormonal changes that occur in women during puberty, menstrual cycle, .....
Convulsions
Seizure or a convulsion is a result of abnormal electrical activity in the brain. If there are two o...
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a d...
Electroencephalogram
An electroencephalogram (EEG) detects electrical activity in the brain using electrodes attached to ...
Epilepsy
Fits or convulsions or Epilepsy is characterized by recurrent, involuntary seizures and is described...
Febrile Fits / Febrile Convulsions
High fever in kids can cause convulsions and are called febrile fits that do not include the seizure...
Melatonin
Melatonin has finally been accepted as effective treatment for insomnia and other sleep disorders. J...
Pancreatitis
Pancreatitis or inflammation of the pancreas may show up as acute pancreatitis or chronic pain. Alco...
Reye’s Syndrome
Reye's syndrome is a medical emergency chiefly affecting children and teenagers and is marked by the...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use