About My Health Careers Internship MedBlogs Contact us
Medindia
LOGIN REGISTER
Advertisement

Endogamy may Raise Infertility Risk in Indian Men

by Iswarya on April 22, 2019 at 5:44 PM
Font : A-A+

Endogamy may Raise Infertility Risk in Indian Men

Deletions of the Y chromosomes which is responsible for the production of sperms may cause infertility in Indian men, reports a new study. The findings of the study are published in the journal Scientific Reports.

The study illustrates how the ethnicity, endogamy and long-time geographical isolation of Indian populations might have played a major role in the high frequencies of deletion events.

Advertisement


According to the researchers, including K. Thangaraj from Centre for Cellular and Molecular Biology, deletions in the AZoospermia Factor (AZF) regions on the human Y chromosome are reported as one of the most common causes of severe testiculopathy and spermatogenic defects leading to male infertility.

For the study, the researchers screened blood samples of 973 infertile men, consisting of 771 azoospermia (complete absence of sperm), 105 oligozoospermia (low sperm count) and 97 oligoteratozoospermia (low sperm count with abnormal shape and size) patients.
Advertisement

The deletion screening was carried out using AZF-specific markers.

The experiments were carried in accordance with the relevant guidelines and regulations approved for research on human samples.

The study revealed deletion events in a total of 29.4 percent of infertile Indian men. Of these, non-allelic homologous recombination events accounted for 25.8 percent.

Indian populations are unique in their origin and have been practicing endogamy for the last two thousand years, and therefore it is important to add a study of the frequencies of AZF deletions on the Y chromosome and their association with fertility in Indian idiopathic infertile men to similar studies from other parts of the world, the researchers said.

Source: IANS
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Emotional Healing
Psychosis Risk Related to Cat Parasite
Sedentary Behavior Precipitates Night-Time Hot Flashes
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
In Vitro Fertilization (IVF) Infertility Vaginitis Egg Donation Artificial Insemination Polycystic Ovarian Syndrome Dilatation and Curettage Varicocele Drugs Causing Sexual Problems Human Anatomy 

Recommended Reading
Genetics of Male Infertility
Encyclopedia section of medindia briefs you about the Genetics of Male Infertility...
In Vitro Fertilization (IVF)
Encyclopedia section of medindia gives a brief introduction to infertility and reproduction...
Infertility
Infertility is a condition wherein couples fail to achieve pregnancy or if the woman has been ......
Prenatal Exposure to DEHP may Result in Male Infertility
Prenatal exposure to platicizers like DEHP may affect male fertility in future generations. DEHP is ...
Artificial Insemination
Artificial Insemination is a medical procedure usually used to treat infertility. In this procedure,...
Drugs Causing Sexual Problems
Sexual problems occur in males as well as in females. Drugs affecting the nervous and our endocrine...
Egg Donation
The term ‘Egg Donation’ is commonly used to refer to the contribution of her eggs by a woman to anot...
Polycystic Ovarian Syndrome
Polycystic ovarian syndrome is the most common hormonal disorder among women of reproductive age an...
Vaginitis
Vaginal infection or vaginitis occurs due to an overgrowth of bacteria or yeast or trichomoniasis ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use