End-of-life Care for People With Kidney Failure Who Undergo Amputation Examined

by Colleen Fleiss on February 20, 2019 at 12:17 PM
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End-of-life Care for People With Kidney Failure Who Undergo Amputation Examined

High levels of healthcare intensity were observed in patients with kidney failure, stated new study. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), indicate that efforts are needed to address the palliative care needs of seriously ill patients with kidney failure who undergo amputation.

However, few studies have sought to describe how commonly patients with ESRD undergo amputation during the final months of life or the kind of care they receive.


To investigate, Catherine Butler, MD (University of Washington School of Medicine, in Seattle) and her colleagues studied a group of Medicare beneficiaries who died in 2002-2014. The analysis included 62,075 beneficiaries with ESRD who did and 692,702 who did not undergo lower extremity amputation in their last year of life, as well as 8,937 beneficiaries without ESRD who did and 949,475 who did not undergo lower extremity amputation.

Overall, 8% of 759,777 beneficiaries with ESRD underwent at least one lower extremity amputation in the last year of life compared with 1% of 958,412 beneficiaries without ESRD. Among patients with ESRD, those who had undergone lower extremity amputation were substantially more likely than those who had not to have been admitted to acute and subacute settings in their last year of life, and to have spent prolonged periods of time in these settings. They were also more likely to have died in the hospital and to have discontinued dialysis treatments before death, yet they spent less time in hospice than other patients with ESRD.

"These findings are concerning because despite wide-spread recognition that lower extremity amputation often means a poor prognosis for patients with ESRD, and that the event should prompt discussion about end-of-life preferences, this study suggests that end-of-life care for these seriously ill patients may not align with the kind of care that many seriously ill patients say they prefer--that is, to die at home and focus on comfort rather than life prolongation," said Dr. Butler. "More work is needed to learn about the experiences of these seriously ill patients with ESRD who undergo amputation and to identify opportunities to improve their care."

In an accompanying Perspective article, Erica Perry, MSW (University of Michigan) and her colleagues noted that not all nephrologists feel comfortable discussing end-of-life options with ESRD patients. "By not openly discussing prognosis when complications mount and quality of life declines, we consign patients to more time in the emergency room, hospital, and ICU. Too often, the result is unnecessary pain and suffering, with death in the hospital rather than a place of the patient's choosing," they wrote. "Our own experience as a renal team suggests that discussing goals and prognosis early in the course of illness fosters ongoing relationships and trust, empowers more informed decisions, and promotes closure at the end of life for patients, families and their renal team as well."

Source: Eurekalert

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