Last week only 15 officers were rostered on to deal with up to 60,000 people in the entertainment precinct - one officer for every 4000 people.
A Central District officer who did not want to be named said they had about the same number of police rostered on Saturday nights as they did weekday mornings.
"We're at the point where we're saying thank God 80 per cent of them are using an illegal drug rather than alcohol, even though in 10 years they'll be suffering manic depressive disorders," News.com.au quoted the officer, as saying.
"But we just couldn't deal with that many people affected by alcohol," he added.
He said police were not able to deliver a satisfactory "level of service" and were flat out responding to calls rather than undertaking preventative actions.
"It is embarrassing. We've sworn an oath to do certain things and we're not being given the resources to achieve that," the officer said.
Drug Arm national communications manager Josie Loth said it was well known that illicit drugs such as ecstasy were much more prevalent in the Valley than other parts of
It's deemed more acceptable than in the city because the Valley's the alternative scene and always has been," Loth said.
She said although ecstasy was a stimulant it tended to relax people but alcohol had the opposite effect.
"When certain people drink . . . it brings out more of a violent tendency, often leading to problems," Loth said.
Australian Medical Association Emergency Department spokeswoman Alex Markwell said alcohol definitely contributed to a lot more injuries than drugs.
"Young men especially can become aggressive on alcohol and get involved in fights and assaults," she said.
"The really common things that we see at the Royal Brisbane and Women's Hospital are head injuries where they've fallen over and hit their heads and we see lots of people with broken hands after hitting people."
"It really is very frustrating from a medical perspective because it chews up our resources. If people didn't drink we wouldn't see anywhere near as many patients as we do," she added.