About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Early-onset Colorectal Cancer is Rising at Alarming Rates in the West

by Adeline Dorcas on May 30, 2019 at 2:21 PM
Font : A-A+

Early-onset Colorectal Cancer is Rising at Alarming Rates in the West

Early-onset colorectal cancer (CRC) is on the rise in Western states, reports a new study. The findings of the study are published in the Journal of the National Cancer Institute.

Early-onset colorectal cancer -cancer occurring before age 50--is rising most rapidly in Western states, where healthy behaviors are prominent, according to a new study. The authors of the study say the findings indicate the need for further etiologic studies to explore early-life colorectal carcinogenesis.

Advertisement


Early-onset colorectal cancer has been on the rise for several decades in the United States for unknown reasons. Because geographic differences could help uncover potential causes for the trend, investigators at the American Cancer Society and The Ohio State University analyzed changes in CRC incidence and risk factors among adults under 50 during 1995-2015 by state and race/ethnicity.

Based on cancer registries representing 95 percent of the US population, the study found early-onset CRC incidence increased over the most recent ten data years (2006-2015) by 1.1 percent per year. Rates rose faster for rectal tumors (1.7% per year) than for colon tumors (0.7% per year).
Advertisement

The increase was mostly confined to whites, among whom rates rose in 40 out of 47 states (with available data) and were otherwise stable. The rise varied in magnitude across states, with average increases exceeding 2.5 percent per year in ten states, six of which are in the West. For example, over the past two decades CRC incidence increased by 73 percent in Washington, from 6.7 (per 100,000) during 1995-1996 to 11.5 during 2014-2015, and by 57 percent in Colorado, from 6.0 to 9.5. Increases were generally steeper for rectal than for colon cancer, with rates doubling in some states (e.g., in Colorado, from 1.9 to 4.2), converging with rates for colon cancer.

"Although early-onset colorectal cancer incidence is currently lowest in Western states and highest in Southern states, consistent with the prevalence of established risk factors, like obesity, physical inactivity, and smoking, this pattern may change because the steepest increases are in Western states," said Rebecca L. Siegel, MPH, American Cancer Society scientific director of surveillance research and lead author of the study.

"This finding suggests that early life exposures, in addition to the 'usual suspects ' may be contributing to the rise in early-onset disease. Future studies should explore novel risk factors for colorectal cancer in young adults."

Source: Eurekalert
Advertisement

Advertisement
Advertisement

Recommended Reading

Latest Cancer News

Exploring the Role of Neutrophils in Immunotherapy
Neutrophils, the blood cell types are mobilized to fight cancer if they are appropriately engaged.
How Can Mouse Avatars Help Treat Multiple Myeloma?
The mouse avatars created help study and develop personalized treatments against blood cancer - myeloma.
Why Is Time of Day Important in Cancer Diagnosis and Treatment?
Chronotherapy (the sleep-wake cycle) is observed as a valuable alternative treatment in cancer diagnosis and treatment.
How Do Neutrophils Impact Pancreatic Cancer Treatment Resistance?
A nanoengineering platform targets neutrophils, the white blood cells without killing pancreatic cancer cells paving the way for effective treatments.
Could TKI Cancer Drugs Lead to Inflammatory Side Effects?
The mechanism by which the kinases cause inflammation has been discovered by scientists.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Early-onset Colorectal Cancer is Rising at Alarming Rates in the West Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests