Early-onset Alzheimer's disease can be identified by a 'cognitive reserve', discovered researchers at the Mayo Clinic in Rochester, Minn. , and PET-CT examinations can identify the disorder.
Researchers learnt that the 'cognitive reserve' inhibited the visible symptoms of early-onset AD, which takes a more aggressive course and progression. Dr. Jacob Richard Hodge, lead researcher for this study, states that with patients with a good background of education, the symptoms manifest themselves late, since the patients are better able to develop coping strategies.
Using earlier PET-CT examination results, the researchers identified significant abnormalities in patients with early-onset AD. This becomes important in the diagnosis of younger patients as Alzheimer's dementia is usually not suspected in a younger age group.