E-cigarette Cannabis Liquid for Medical Use is Safer Than a Joint, Better Than Pill

by Dr. Trupti Shirole on  May 27, 2016 at 9:41 AM Research News
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Battery-powered e-cigarettes heat up liquids containing artificial flavorings, with or without nicotine, to release a vapor which is inhaled and exhaled much like smoke. They are touted as safer than the real thing, and an aide for giving up cancer-causing tobacco - which is also an ingredient of the traditional cannabis joint.
 E-cigarette Cannabis Liquid for Medical Use is Safer Than a Joint, Better Than Pill
E-cigarette Cannabis Liquid for Medical Use is Safer Than a Joint, Better Than Pill

Medical marijuana can be legally prescribed in some countries for pain relief, appetite stimulation, nausea reduction or the relief of muscle spasms. Swiss scientists have taken a leaf from the pothead recipe book to brew an e-cigarette cannabis liquid for medical use. The scientists said that it is safer than a joint and better than a pill.

'Therapeutic cannavaping', they argued, should be examined as an alternative to existing treatments which can come in the form of a syrup, pill, mouth spray, skin patch, suppository, or a plain-old spliff. The team copied an improvised method popular among marijuana afficionados using butane gas to extract and concentrate cannabinoids - the active, high-causing compounds of cannabis.

"We were inspired by what is done illegally, underground, on the web fora," study co-author Vincent Varlet, a biochemist and toxicologist from the University Center of Legal Medicine in Lausanne, Switzerland, told AFP. "Normally, they use this form of cannabinoids to get high. Based on what is done illegally, we found that it could be interesting for the medical field."

The method yields super-concentrated 'dabs' of butane hash oil (BHO) - comprising about 70-80% THCa - the precursor of THC or tetrahydrocannabinol, which is the psychoactive ingredient. THCa is transformed into THC at high heat.

Usually the dabs are burnt and the fumes inhaled. But for the study, the team mixed their activated BHO paste into commercially-available e-cigarette liquid at different concentrations - three, five or 10%. They then put 'vaping machines' to work: sucking at the e-cigarettes and blowing out vapor, which was measured for its THC content, according to results published in the journal Scientific Reports.

"Cannavaping appears to be a gentle, efficient, user-friendly and safe alternative method for cannabis smoking for medical cannabis delivery," the team concluded with a nod to 'the creativity of cannabis users'. "It was also more reliable than consuming cannabinoid pills or foods which are poorly and erratically absorbed," said Varlet.

Cannabis-infused e-liquids are advertised online, along with a rash of recipes for making your own.

"A challenge," said Varlet, "was to keep cannabis intended for therapeutic use out of the hands of recreational high-seekers." One way to do that was to have legal drugs with microdoses of cannabinoids.

"We have calculated that to have the same dose of what is present in a real cigarette joint. With tobacco, we have to vape between 80-90 puffs of the 10% BHO liquid," said Varlet. "80 puffs constitutes a rebuttal to getting high," he added, when a few drags from a joint will do.

"The take-home message of our article is that vaping is less harmful than smoking, so you can be sure that cannavaping is less harmful than cannabis smoking for medical purposes," said Varlet, adding there was no plan to patent or sell the product. "Today, we have set the cat among the pigeons. This is just the first step, and we need to see how the scientific community is going to welcome this kind of possibility."

"Whilst vaping cannabis substances does indeed remove the harmful effects of tobacco smoke, my concerns about vaping cannabis would be around the use of flavored cannabis e-cigarettes that could be more popular among younger people," said Michael Bloomfield, a psychiatry lecturer at University College London.

David Nutt of Imperial College London said it was a 'great idea, but would be illegal in the UK currently'.

Source: AFP

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