Membrane vesicles, which are essential for the trafficking of materials across nerve cells, may be an important factor in the pathology of Alzheimer's disease, according to new research from NYU Langone Medical Center.
The study conducted by Dr. Ralph Nixon, Professor of Psychiatry and Cell Biology, and Ph.D student Seonil Kim showed that mouse neurons that over-produce a precursor to the amyloid protein closely linked to Alzheimer's disease development were unable to shuttle the vesicles to their proper destinations in nerve cells, causing them instead to enlarge abnormally and accumulate.
Alzheimer’s disease - Causes, Symptoms, Diagnosis, Stages, Types, Prevention, Prognosis & Treatment
Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and making the person increasingly dependent on others.
Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and making the person increasingly dependent on others.
They said that disrupted transport of the vesicles could lead to the neurodegeneration of Alzheimer's disease.
A presentation on the study was made at the ongoing Alzheimer's Association 2008 International Conference, which ends on July 31 in Chicago.
About Schizophrenia
Schizophrenia is a mental disorder characterized by symptoms of thought, behavior and social problems.
Schizophrenia is a mental disorder characterized by symptoms of thought, behavior and social problems.
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Partial Amyloid Beta Inhibition Improves Memory in Alzheimer's
An animal study conducted by New York University researchers suggests that partially inhibiting an enzyme that initiates the release of amyloid beta may help improve memory dysfunction.
An animal study conducted by New York University researchers suggests that partially inhibiting an enzyme that initiates the release of amyloid beta may help improve memory dysfunction.
The Lancet Says Dementia in Developing World 'Substantially' Underestimated
A new study, led by researchers from King's College London, has shown that cases of dementia in the developing world are far more prevalent than previously thought, suggesting that
A new study, led by researchers from King's College London, has shown that cases of dementia in the developing world are far more prevalent than previously thought, suggesting that
