
Adolescents with moderate-to-severe atopic dermatitis or eczema could benefit from Dupilumab, according to results of a phase IIa open-label trial and a subsequent phase III open-label extension trial.
The results from these latest studies, which are reported in the British Journal of Dermatology, demonstrate the long-term safety and efficacy of the medication for up to 52 weeks of treatment.
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Dupilumab works by stopping the action of certain substances in the body that cause the symptoms of eczema. Specifically, it is a monoclonal antibody against interleukin-4 receptor alpha.
"Results from these trials show that dupilumab provides substantial and sustained clinical benefit to these patients with an acceptable safety profile."
Source: Eurekalert