The potency and safety of drugs may be predicted with the help of near-infrared chemical imagine, recent research finds.
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a drug, reaction to a drug or drug abuse.
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‘According to this study, near- infrared chemical imaging can help maintain the safety of pharmaceutical tablets.’
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Process Analytical Technology (PAT) has been of great value to pharmaceutical manufacturing, enabling testing throughout the manufacturing process and allowing the real-time release of the finished product. Often, the final step in the production is tableting. In this, a die used to compress the tablet is filled with powder via a feed frame, that ensures a constant supply of material. The powder contains the active pharmaceutical ingredient (API) as well as other material required for the production of the tablet. Subject to the mechanical processes within the feed frame, the consistency of the powder varies due to density variations and segmentation. Such inconsistencies can lead to differences in concentrations of the API in individual tablets. Too much or too little API in a tablet are each dangerous for the patient taking the medicine.
These variations in powder flow phenomena in pharmaceutical manufacturing feed frames have previously been investigated with near-infrared (NIR) spectroscopy. However, whilst this has provided useful information, due to the comparatively small area analyzed with this technique, areas of segregation can be missed.
![Choose The Right Over-the-Counter Drugs for Allergy]( "Choose The Right Over-the-Counter Drugs for Allergy")
Over-the-counter (OTC) drugs can be bought without a prescription. OTC allergy medications are for the allergy sufferer to choose the right over-the-counter drugs.
According to Ryan Gosselin, Associate Professor in the Department of Chemical Engineering and Biotechnology Engineering of the Université de Sherbrooke, Québec, Canada, "concentration predictions with NIR chemical imaging were found to be similar to those of the NIR spectroscopy model. However, NIR chemical imaging is better positioned to view concentration modifications over larger sample areas, and different image sections can be analyzed separately in the event of localized concentration changes."
Source: Eurekalert
Choose The Right Over-the-Counter Drugs for Allergy
Over-the-counter (OTC) drugs can be bought without a prescription. OTC allergy medications are for the allergy sufferer to choose the right over-the-counter drugs.
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According to Ryan Gosselin, Associate Professor in the Department of Chemical Engineering and Biotechnology Engineering of the Université de Sherbrooke, Québec, Canada, "concentration predictions with NIR chemical imaging were found to be similar to those of the NIR spectroscopy model. However, NIR chemical imaging is better positioned to view concentration modifications over larger sample areas, and different image sections can be analyzed separately in the event of localized concentration changes."
Source: Eurekalert
Drug Delivery System
Drug delivery systems, is a technology using various chemicals to bind the target drugs, carry them to target organ, tissue or cell where the drug is released at a pre-determined rate.
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 Drugs in Pregnancy and LactationDuring pregnancy & lactation a nutritious diet, suitable exercise, adequate rest and a tranquil mind help both the mother and fetus and drugs should be avoided. | Advertisement
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