A new drug could be the means to reduce tumours dramatically in lung cancer patients, states a study.
The new drug, Crizotinib, under development by Pfizer, showed dramatic results in reducing lung cancer tumours in some patients during Phase I and II clinical trials.
Phase I/II clinical trials demonstrated that 57 percent of patients had their tumours reduced and at eight weeks of the treatment, 87 percent showed disease stabilization.
In some patients with non-small cell lung cancer (NSCLC), fusion of anaplastic lymphoma kinase (ALK) gene and EML4 gene promotes lung cancer cell growth, especially if they have adenocarcinoma subtype of lung cancer. Crizotinib inhibits the enzyme, allowing the cancer cells to die off.