Drug Found to Increase the Risk of Inflammatory Bowel Disease

by Ramya Rachamanti on  July 4, 2019 at 5:05 PM Drug News
RSS Email Print This Page Comment bookmark
Font : A-A+

Anti-TNFα agents were essential in the management of various autoimmune diseases, but paradoxically, they found to initiate the development of other autoimmune conditions.
Drug Found to Increase the Risk of Inflammatory Bowel Disease
Drug Found to Increase the Risk of Inflammatory Bowel Disease

In an Alimentary Pharmacology & Therapeutics study of 17,018 individuals with autoimmune diseases who were treated with anti-TNFα medications--mostly infliximab, etanercept, and adalimumab--and 63,308 individuals who were not, treatment with etanercept, but not other antiTNFα agents, was linked with an elevated risk of developing inflammatory bowel disease: a twofold increased risk of Crohn's disease and a twofold increased risk of ulcerative colitis.

Show Full Article


"This study established that there is an increased risk of developing inflammatory bowel disease in individuals taking etanercept. Recognition of this phenomenon is important for clinicians taking care of these patients," said lead author Joshua Korzenik, MD, of Brigham and Women's Hospital, in Boston. "Perhaps more importantly, this study suggests that inflammatory bowel disease may be one of the auto-immune diseases that can be provoked by anti-TNFα agents. This suggests that there may be a common mechanism of immune dysregulation underpinning these diseases."



Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Drug Toxicity Colo-rectal cancer - Management Signature Drug Toxicity Crohns Disease Drugs Banned in India Inflammatory Bowel Disease Foul Smelling Stool Neck Cracking 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive