Medindia LOGIN REGISTER
Medindia
Advertisement

Drug Eluting Stents Have Delayed Adverse Events

by Julia Samuel on March 19, 2015 at 3:03 PM
Drug Eluting Stents Have Delayed Adverse Events

A team of researchers designed a study to find out if there was a difference between two treatments for heart disease and the outcomes it produces.

A drug eluting stent, a coronary stent placed into narrowed arteries that slowly released drugs, was compared with a bare metal stent (does not carry the drug) with an externally administered drug, thienopyridine.

Advertisement

A set of treatments was compared to find the rate of thrombosis, adverse cardiac events or bleeding in patients. Bare metal stent (BMS) placement following elective percutaneous coronary intervention (PCI) such as stent placement and 1 month of DAPT was compared with 6 to 12 months for drug-eluting stents (DES).

Dean J. Kereiakes, the Christ Hospital Heart and Vascular Center, Cincinnati, and Laura Mauri, Harvard Clinical Research Institute and Brigham and Women's Hospital, Boston, and colleagues randomly assigned 11,648 patients who received a bare metal stent or drug eluting stent. The patients were treated with aspirin and completed 12 months of dual antiplatelet therapy (DAPT) without bleeding or ischemic events. Further, they were prescribed thienopyridine or placebo at months 12 through 30.
Advertisement

Moderate or severe bleeding was less in the placebo but the rate of thrombosis and major cardiac events in the patients who continued thienopyridine was less than the placebo. Similarly, thrombosis rate and major cardiac events were fewer in BMS than DES while bleeding was more in BMS. The results comparing continued thienopyridine vs placebo in the cohort treated with DES demonstrated significant reductions in stent thrombosis and major cardiac events.



Source: Medindia
Font : A-A+

Advertisement

Advertisement
Advertisement

Recommended Readings

Latest Research News

Confronting the Painful Realities of Racial Bias in Health
Painful realities of racial discrimination and bias are increasingly acknowledged as harmful to the well-being.
Intricate Dance of Flaxseed, Gut Microbiome, and Breast Cancer Genes
Role of flaxseed in the relationship between gut microorganisms and mammary gland microRNAs has been uncovered by a new study.
MRNA Therapy's Promise for Chronic and Acute Liver Disease
New mRNA stem cell therapy, akin to COVID-19 vaccine tech, shows potential against chronic and acute liver diseases.
Could Light Therapy Be a Breakthrough for Alzheimer's?
Light therapy enhances sleep and psycho-behavioral symptoms in Alzheimer's patients with minimal side effects.
Does Twice Daily Stimulation Enhance Alzheimer's Mental Functions?
Electrical stimulation improves Alzheimer's patients' cognitive function and correlates with restored cortical plasticity.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Drug Eluting Stents Have Delayed Adverse Events Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests