A team of researchers designed a study to find out if there was a difference between two treatments for heart disease and the outcomes it produces.
A drug eluting stent, a coronary stent placed into narrowed arteries that slowly released drugs, was compared with a bare metal stent (does not carry the drug) with an externally administered drug, thienopyridine.
Lifestyle Paths to Heart Disease
Heart disease can be of many types depending upon whether they involve the heart muscles or artery walls or heart beats. Bad lifestyle choices contribute to heart disease.
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A set of treatments was compared to find the rate of thrombosis, adverse cardiac events or bleeding in patients. Bare metal stent (BMS) placement following elective percutaneous coronary intervention (PCI) such as stent placement and 1 month of DAPT was compared with 6 to 12 months for drug-eluting stents (DES).
Dean J. Kereiakes, the Christ Hospital Heart and Vascular Center, Cincinnati, and Laura Mauri, Harvard Clinical Research Institute and Brigham and Women's Hospital, Boston, and colleagues randomly assigned 11,648 patients who received a bare metal stent or drug eluting stent. The patients were treated with aspirin and completed 12 months of dual antiplatelet therapy (DAPT) without bleeding or ischemic events. Further, they were prescribed thienopyridine or placebo at months 12 through 30.
![Diet, Lifestyle and Heart Disease]( "Diet, Lifestyle and Heart Disease")
The correlation between diet, lifestyle and heart disease. The importance of balanced diet life style and exercise for controlling heart disease.
Moderate or severe bleeding was less in the placebo but the rate of thrombosis and major cardiac events in the patients who continued thienopyridine was less than the placebo. Similarly, thrombosis rate and major cardiac events were fewer in BMS than DES while bleeding was more in BMS. The results comparing continued thienopyridine vs placebo in the cohort treated with DES demonstrated significant reductions in stent thrombosis and major cardiac events.
Source: Medindia
Diet, Lifestyle and Heart Disease
The correlation between diet, lifestyle and heart disease. The importance of balanced diet life style and exercise for controlling heart disease.
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Moderate or severe bleeding was less in the placebo but the rate of thrombosis and major cardiac events in the patients who continued thienopyridine was less than the placebo. Similarly, thrombosis rate and major cardiac events were fewer in BMS than DES while bleeding was more in BMS. The results comparing continued thienopyridine vs placebo in the cohort treated with DES demonstrated significant reductions in stent thrombosis and major cardiac events.
Source: Medindia
Coronary Balloon Angioplasty
Coronary balloon angioplasty is an interventional procedure wherein blood flow is restored in a blocked blood artery supplying the heart.
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 New Approach: Aortic Valve Implantation Combined With Coronary Artery StentingAortic stenosis is a condition where the valve at the junction of the left ventricle and the aorta, the largest blood vessel of the body, is narrowed. | Advertisement
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