The problem of obtaining functional donor kidneys is a common one the world over and researchers are always looking at ways to streamline the process.
A pilot study of a system for harvesting kidneys from non-heart-beating donors where attempts of resuscitation after a witnessed out-of-hospital cardiac arrest have failed (uncontrolled NHBDs) resulted in 21 successful kidney transplants - a 10% increase in the transplantation rate - over 17 months.
Researchers writing in BioMed Central's open access journal Critical Care have shown that retrieval from uncontrolled NHBDs may provide a valuable source of organs and could help counter the shortage of kidney grafts in France.
Between February 1st 2007 and June 30th 2008, 122 patients were referred to the hospital in this way, and 49 were found to be eligible for organ retrieval. The families of 15 of these patients refused consent for organ donation, in 12 cases in the absence of or contrary to the donor's previously expressed wishes. From the remaining patients, 31 kidneys were transplanted and at least 27 of these transplants were ultimately successful.
According to Losser, the procedure raised ethical controversies in France, "The question emerged about a conflict of interest between patient care and potential organ procurement. In fact, in this cohort, resuscitation duration was always longer than recommended. There is, however, a clear need for better acceptance of organ donation within the population, something that could be achieved by sustained nationwide information campaigns".