About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Doctors Without Borders Urge South Africa to Allow Generic Version of HIV Drugs

by Reshma Anand on October 29, 2015 at 12:58 PM
Font : A-A+

Doctors Without Borders Urge South Africa to Allow Generic Version of HIV Drugs

Thousands of patients suffering with HIV/ AIDS are sent back home without drugs as the pharmaceutical company AbbVie refuses to license patent to generic companies, said the Médecins Sans Frontières.

After six months of persistent supply problems with the key HIV medicine lopinavir/ritonavir (LPV/r), Médecins Sans Frontières (MSF) urged the South African government to put the public's health first and override pharmaceutical company AbbVie's patent with a 'compulsory license,' in order to allow generic versions of LPV/r to be used in the country.

Advertisement

AbbVie, which markets LPV/r as 'Aluvia', is the sole supplier in South Africa for a medicine which is a life-line for nearly 10% of the country's approximately three million people on HIV treatment. In the majority (65%) of LPV/r stock out cases reported by patients or health care workers in South Africa since April 2015 to date, patients were sent away with no medicine, and in 35% of cases, people were sent away with insufficient supply. According to a consortium monitoring medicine stock outs in South Africa, the stock outs were wide spread and acute - about 10% of facilities, mostly large district hospitals, had more than 500 patients per facility being affected.

"People are being turned away from clinics without medicine and are being asked to purchase it on the private market. Many simply cannot afford it and this causes distress. Alarmingly, people without access to treatment over time can become resistant to lopinavir/ritonavir and require more expensive medicines - they also risk falling sick and could even die," said Dr. Amir Shroufi, MSF's Deputy Medical Coordinator in South Africa.
Advertisement

To assess the current situation, a separate rapid survey was conducted in October, with 12% of 796 responding facilities experiencing an ongoing LPV/r stock out. In over 50% of these cases, the duration of the stock out was longer than 30 days.

Several producers of LPV/r, other than AbbVie, have quality-assured generic versions of the drug registered in South Africa, or have filed for registration of other ritonavir-based treatments that the World Health Organization suggests could be used as an alternative to LPV/r. AbbVie's patents prevent the use of generic versions of LPV/r in South Africa, and the company has refused to provide voluntary licenses to the Medicines Patent Pool which could improve security of LPV/r supply in developing countries.

"Since AbbVie has refused to act appropriately to ensure that patients obtain the medicines they need to stay healthy and alive, the South African government should be compelled to take action. The government should take steps to ensure that the company's patents no longer block people from getting this essential drug from other suppliers," said Dr. Shroufi.

LPV/r is protected by multiple patents in South Africa, but the Department of Health has the authority to allow generic manufacturers to supply patented medicines when patent holders like AbbVie are not meeting demand. The process of issuing a compulsory license has been carried out in numerous countries, such as Brazil and India, to improve access to life-saving medicines.

"With thousands of lives hanging in the balance, the challenges of overcoming LPV/r patent barriers to resolve the current crisis must not prevent the government from taking action. Many of the patent-related problems that have led to shortages of LPV/r could have been avoided if South Africa stopped blindly handing out patents, and had more pro-public health laws in place," said Catherine Tomlinson, of MSF's Access Campaign in South Africa.

"If South Africa examined patent applications, LPV/r might not have been granted multiple patents for a prolonged patent monopoly, and if the process for issuing compulsory licenses were less onerous, alternative suppliers could have been on the market years ago," he added.

A process to reform South Africa's patent law has been underway at the Department of Trade and Industry (DTI) since 2009. Two years after the public comment period closed on a draft national intellectual property policy, the DTI has failed to finalize it or embark on proposed reform of the Patents Act.

"MSF calls on the government to take action now: issue a compulsory license so generic versions of lopinavir/ritonavir can be imported or produced in-country. The South African government must urgently amend the country's patent laws so people don't go without the medicines they need in the future," said Tomlinson.

Source: Medindia
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Quiz on Low-Calorie Diet for Diabetes
World Heart Day in 2022- Use Heart for Every Heart
Anemia among Indian Women and Children Remains a Cause of Concern- National Family Health Survey-5
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Oral Health And AIDS Drug Toxicity AIDS/HIV AIDS/HIV - Epidemiology AIDS/HIV - Clinical Features AIDS/HIV - Health Education AIDS/HIV - Prevention And Transmission AIDS / HIV - Treatment AIDS/HIV- Lab Tests and Faqs Prostitution: Fresh Stakes in the Oldest Trade 

Most Popular on Medindia

Daily Calorie Requirements Drug - Food Interactions Find a Hospital Sinopril (2mg) (Lacidipine) Post-Nasal Drip Blood - Sugar Chart Iron Intake Calculator Accident and Trauma Care Sanatogen Diaphragmatic Hernia
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Doctors Without Borders Urge South Africa to Allow Generic Version of HIV Drugs Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests