Individuals chance for developing malaria depends on their metabolic state, which could be controlled by external stimuli like dietary patterns, reveals a new study.
The progression and development of an infectious disease is directly dependent not only on the characteristics of the causing infectious agent but also on the genetic characteristics of the host, which also dictate the efficiency of the infection.
Malaria
Malaria is caused by a parasite that enters blood through the bite of an infected mosquito. It is characterized by fever, vomiting, shivering, sweating and other symptoms.
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‘Dietary shifts increase the levels of pro-oxidants, which aid in reducing parasite load and thereby, lowering the severity of the disease.’
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The research team from Instituto de Medicina Molecular (iMM) Lisboa conducted the study.
During the last years scientific discoveries have suggested that external factors independent of the host-parasite dichotomy, such as eating habits, can impact in the establishment, progression and endpoint of infections.
![Malaria - Protection Strategies]( "Malaria - Protection Strategies")
Malaria is a dangerous disease with lethal consequences that requires protective measures for prevention and control of malaria in endemic regions of the world.
The team, led by Maria Mota, manipulated the diet fed to lab mice for very short periods of time and evaluated the level of infection caused by the malaria parasite.
The results, now published in the prestigious journal Nature Microbiology, show that an increase in the levels of pro-oxidants caused by dietary shifts leads to a 90 percent reduction in parasite load during the hepatic phase of the infection and consequently lowers the severity of the disease.
The mechanism used by the host to eliminate the malaria parasite, now revealed in this study, may contribute to explain how certain genetic alterations associate to high levels of oxidative stress, such as sickle-cell anaemia or beta thalassemia, have been selected in the population due to their protective effect against malaria.
Source: Eurekalert
Malaria - Protection Strategies
Malaria is a dangerous disease with lethal consequences that requires protective measures for prevention and control of malaria in endemic regions of the world.
Advertisement
The team, led by Maria Mota, manipulated the diet fed to lab mice for very short periods of time and evaluated the level of infection caused by the malaria parasite.
The results, now published in the prestigious journal Nature Microbiology, show that an increase in the levels of pro-oxidants caused by dietary shifts leads to a 90 percent reduction in parasite load during the hepatic phase of the infection and consequently lowers the severity of the disease.
The mechanism used by the host to eliminate the malaria parasite, now revealed in this study, may contribute to explain how certain genetic alterations associate to high levels of oxidative stress, such as sickle-cell anaemia or beta thalassemia, have been selected in the population due to their protective effect against malaria.
Source: Eurekalert
Malaria - Waterborne
Encyclopedia section of medindia gives general information about About Malaria Causes
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 Mosquito DiseasesMosquito-borne diseases, like malaria, filaria, dengue, etc are common in places conducive of mosquito breeding. Swamps, ponds and stagnated drainage provide optimal breeding ground for mosquitoes. | Advertisement
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