About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Diabetic Wound Healing A Lot Faster Using Human Umbilical Cord Blood Cells

by Tanya Thomas on February 25, 2011 at 9:46 AM
Font : A-A+

 Diabetic Wound Healing A Lot Faster Using Human Umbilical Cord Blood Cells

Korean scientists have found that transplanting human umbilical cord blood-derived endothelial progenitor cells (EPCs) 'significantly accelerate' wound closure in diabetic mouse models.

Diabetes is often associated with impaired wound healing, according to study's corresponding author, Wonhee Suh of the CHA University Stem Cell Institute.

Advertisement

"EPCs are involved in revascularization of injured tissue and tissue repair," said Suh.

"Wounds associated with diabetes that resist healing are also associated with decreased peripheral blood flow and often resist current therapies.
Advertisement

"Normal wounds, without underlying pathological defects heal readily, but the healing deficiency of diabetic wounds can be attributed to a number of factors, including decreased production of growth factors and reduced revascularization," he said.

For the study, the researchers transplanted EPCs into an experimental group of mice modeled with diabetes-associated wounds, but did not transplant EPCs into a control group.

They found that the EPCs "prompted wound healing and increased neovascularization" in the experimental group.

"The transplantation of EPCs derived from human umbilical blood cells accelerated wound closure in diabetic mice from the earliest point," said Suh.

The researchers found that growth factors and cytokines (small proteins secreted by specific cells of the immune system) were "massively produced" at the wounded skin sites and contributed to the healing process.

The study has been published in the current issue of Cell Transplantation.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Diet and Oral Health: The Sugary Connection May Become Sour
World AIDS Day 2022 - Equalize!
Test Your Knowledge on Sugar Intake and Oral Health
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Stem Cells - Cord Blood Thalassemia Stem Cells - Fundamentals Parkinsons Disease Surgical Treatment Diabetes - Self-Monitoring of Blood Glucose (SMBG) Diabetes and Exercise Pregnancy and Complications Benefits of Meditation / Meditation Therapy Type 2 Diabetes Decoding HbA1c Test for Blood Sugar 

Most Popular on Medindia

Indian Medical Journals Diaphragmatic Hernia Drug Side Effects Calculator Calculate Ideal Weight for Infants Find a Hospital Drug Interaction Checker Nutam (400mg) (Piracetam) Turmeric Powder - Health Benefits, Uses & Side Effects Noscaphene (Noscapine) Selfie Addiction Calculator
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Diabetic Wound Healing A Lot Faster Using Human Umbilical Cord Blood Cells Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests