About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Depression may Diminish Benefits of Healthy Behaviors: Study

by Sheela Philomena on March 27, 2013 at 2:53 PM
Font : A-A+

 Depression may Diminish Benefits of Healthy Behaviors: Study

Depression may inhibit the anti-inflammatory effects linked with fitness and light-to-moderate alcohol consumption, suggests study conducted by researchers at Duke Medicine.

The finding - based on measurements of the cardio-metabolic risk marker C-reactive protein (CRP) - points to another potential danger of depression.

Advertisement

"Our findings suggest depression not only directly affects an individual's mental and physical health; it might also diminish the health benefits of physical activities and moderate alcohol consumption," said lead author Edward C. Suarez, PhD, associate professor of psychiatry and behavioral sciences at Duke Medicine.

"This appears to be specific to inflammation, which we know increases the risk for heart disease, so our findings suggest that depression could be a complicating risk factor," he added.
Advertisement

CRP is a biomarker that predicts future risk of heart disease and other chronic inflammatory conditions. It may also play a role in the formation of plaque that builds up in arteries.

Physical activity and moderate alcohol consumption, defined as one drink a day for women and two a day for men, have each been shown to lower the risk of cardiovascular disease and type 2 diabetes. These behaviors also reduce inflammation, which is demonstrated through lower levels of CRP.

In contrast, depression is associated with elevated CRP and increased risk of heart disease and type 2 diabetes.

In the current study, researchers gathered information from 222 nonsmoking, healthy adults with no history or diagnosis of psychiatric conditions. They recorded the amount of alcohol the participants consumed, defining light-to-moderate drinking as about half a drink per day for women and one daily drink for men.

Participants reported how many hours of physical activity they did in the past week in activities such as walking, playing tennis, and exercise classes. Researchers also measured CRP levels through blood samples and evaluated the participants' depressive symptoms, with 4.5 percent of the study group meeting the criteria for depression.

The researchers found that untreated depression hindered the anti-inflammatory effects of moderate alcohol consumption and exercise. Participants who were physically active generally had lower CRP levels, with the exception of those who were depressed, who saw no beneficial effect on CRP levels.

In addition, light-to-moderate alcohol consumption was associated with lower CRP, but only in men who were not depressed. Men with symptoms of depression did not see the benefits of light-to-moderate alcohol consumption. Depression did not make a statistically significant difference among women who consumed light to moderate amounts of alcohol, nor those who didn't drink or only drank infrequently.

"This is a novel finding, and it seems to be specific to inflammation as measured by CRP," Suarez said, given that depression did not affect other health markers such as fasting triglyceride and cholesterol levels.

Although preliminary, Suarez said the study could guide health care providers on how best to reduce the risk of heart disease and type 2 diabetes. In addition to traditional recommendations to increase physical activity and adhere to a Mediterranean diet that includes alcohol consumption, clinicians may also need to consider the mental state of their patients and specifically the presence of depressive symptoms.

This combined approach could be especially beneficial for primary care providers, who are in a good position to both screen for depressive symptoms and measure CRP and cardiovascular risk. Early intervention - and perhaps more aggressive treatment for depression - may benefit patients who do not see the benefit of heart-healthy activities due to untreated depression.

"We're not saying that exercise isn't helpful for those with depression; what we saw is that depression has effects beyond what has previously been reported. Even if mental health improves, the anti-inflammatory benefits of physical activities may lag behind," Suarez said.

Future longitudinal studies could measure CRP levels among those with depression to see if the anti-inflammatory effects of healthy behaviors catch up over time.

Study results were recently published online in the journal Brain, Behavior, and Immunity.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
Long-Term Glycemic Control - A Better Measure of COVID-19 Severity
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Adolescence Depression Depression Stress Relief Through Alternative Medicine Andropause / Male Menopause Pregnancy and Complications Bereavement Holistic Management for Depression Tourette Syndrome Dealing with Menopause symptoms through lifestyle changes Tired All The Time 

Recommended Reading
Holistic Management for Depression
Depression is a common disorder and many worldwide suffer from depression. Early recognition of ......
Depression
Depression is one of the most common mental disorders affecting approximately 340 million people in ...
Quiz on Depression
The World Health Organization reports that depression is one of the main causes of disability ......
Foods to Beat Depression
Depression can be a severe mental health problem that can lead to other health issues. Find top ......
Andropause / Male Menopause
Andropause or male menopause causing low libido in a man is due to decreasing level of male hormones...
Bereavement
Bereavement refers to grief, pain and sadness following the loss of a loved one, especially during t...
Dealing with Menopause symptoms through lifestyle changes
You can deal with menopause symptoms such as hot flashes, weight gain and forgetfulness by making si...
Pregnancy and Complications
In-depth guide for expecting mothers to overcome health complications related to early or late pregn...
Tired All The Time
Tired All The Time (TATT) syndrome is not only about feeling of tired, however there are a host of o...
Tourette Syndrome
Tourette syndrome (TS) is a neurological disorder wherein the affected person makes repetitive and s...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use