Researchers have discovered a way to effectively deliver staurosporine (STS), a powerful anti-cancer compound that has vexed researchers for more than 30 years due to its instability in the blood and toxic nature in both healthy and cancerous cells.
Scientists Identify Gene Variant That Ups Risk of Colorectal Cancer from Eating Red Meat
A common genetic variant that affects 1 in 3 people significantly increases the risk of colorectal cancer from the consumption of red meat and processed meat has been discovered by scientists.
A common genetic variant that affects 1 in 3 people significantly increases the risk of colorectal cancer from the consumption of red meat and processed meat has been discovered by scientists.
STS was originally isolated from the bacterium Streptomyces staurosporeus in 1977. The compound prompts a wide variety of cancer cell types to self-destruct, a process called apoptosis or programmed cell death. In its free form, STS is quickly metabolized and harmful to healthy cells. By trapping STS in tiny spheres called liposomes, Moores Cancer Center researchers have been able to effectively deliver the compound, past healthy tissue, to the tumor, with potent results.
Liposomes are microscopic bubbles made from the same molecules as cell membranes. Researchers use these hollow spheres to deliver therapeutic agents. Anti-cancer drugs can be loaded inside, while disguising agents coat the external membrane surface to hide the cancer-killer from the immune system.
Researchers Develop New Idea for Targeting the Common Cancer Protein KRAS
Study finds patients with cancers driven by the protein KRAS, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex.
Study finds patients with cancers driven by the protein KRAS, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex.
Diabetes Drug Along With Chemo and Radiation may Improve Outcomes in Lung Cancer Patients
Metformin along with radiation and chemotherapy may slow lung tumor growth and recurrence, suggests study.
Metformin along with radiation and chemotherapy may slow lung tumor growth and recurrence, suggests study.
Coffee Consumption Cuts Liver Cancer Risk
Three cups of coffee per day can reduce the risk of hepatocellular carcinoma (HCC) by more than 50 percent, reveals study.
Three cups of coffee per day can reduce the risk of hepatocellular carcinoma (HCC) by more than 50 percent, reveals study.
