About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Connection Between Frailty and Survival After a Lung Transplant

by Bidita Debnath on December 19, 2015 at 2:01 AM
Font : A-A+

Connection Between Frailty and Survival After a Lung Transplant

Frailty, defined simply as "an increased vulnerability to adverse health outcomes," it can affect a patient's chances of surviving a surgical procedure or needing a nursing home. Frailty can affect people of all ages and demographics.

A new study from physicians at Mayo Clinic in Rochester, Minn., published recently in the Journal of Heart and Lung Transplantation, is among the first to show a definitive connection between frailty and survival after a lung transplant procedure. Mayo Clinic researchers studied 102 individuals who received lung transplants at Mayo Clinic between Jan. 1, 2002, and Dec. 31, 2013, and found that patients who were frail had a decreased survival rate compared to patients who were not frail.

Advertisement


According to the report, 46 percent of the patients studied were considered to be frail based on an assessment of 14 activities of daily living, such as difficulty climbing stairs, dependency on oxygen or noninvasive ventilation for normal breathing and difficulty with housekeeping chores. Of those considered to be frail, 63 percent were female with an average age of 57. Within this study population, there were 32 deaths within the first three years post-transplant.

"Based on this population, we saw a definitive association between pre-transplant frailty and decreased survival after transplantation," says Cassie Kennedy, M.D., Pulmonology and Critical Care Medicine, Mayo Clinic. "This suggests that we may be able to help patients live longer with fewer complications after a transplant by intervening early to prevent or lessen the severity of frailty."
Advertisement

According to Dr. Kennedy, Mayo Clinic researchers found that the one-year survival rate for frail patients was 71.7 percent, compared to 92.9 percent for patients who were not frail. At three years, the survival rate for frail patients was 41.3 percent, compared to 66.1 percent for patients who were not frail.

"Understanding the connection between frailty and lung transplant survival and outcomes can help physicians deliver a more accurate prognosis for transplant patients and, ultimately, get patients and their families engaged in taking steps to improve long-term outcomes and survival," says Dr. Kennedy.

Kennedy adds that future studies in this area will more clearly define the role that frailty plays in identifying candidates for lung transplantation, with the potential to influence selection guidelines and transplant center policies.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Test Your Knowledge on Kidney
World Disability Day 2022 - The Role of Innovative Transformation
Diet and Oral Health: The Sugary Connection May Become Sour
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Amyotrophic Lateral Sclerosis (ALS) Pneumoconiosis Pulmonary Arterial Hypertension Silicosis 

Most Popular on Medindia

Color Blindness Calculator Blood Donation - Recipients Accident and Trauma Care Sanatogen Drug Side Effects Calculator Loram (2 mg) (Lorazepam) Find a Doctor Selfie Addiction Calculator Iron Intake Calculator Daily Calorie Requirements
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Connection Between Frailty and Survival After a Lung Transplant Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests